Results 211 to 220 of about 96,379 (348)
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada+2 more
wiley +1 more source
Clozapine reduced symptoms and side effects in patients who had refractory schizophrenia [PDF]
Peter B. Jones
openalex +1 more source
Clozapine rechallenge after clozapine-induced myocarditis: A case report to validate a previously published protocol. [PDF]
Russell SJ+3 more
europepmc +1 more source
Clozapine – a survey of patient perceptions [PDF]
David Taylor+4 more
openalex +1 more source
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett+4 more
wiley +1 more source
Impact of <i>CYP1A</i>, <i>CYP2C19</i>, <i>CYP2D6</i>, <i>CYP3A4</i>, <i>CYP3A5</i>, and <i>NFIB</i> genotypes on clozapine serum concentration in smokers and nonsmokers. [PDF]
Lenk HÇ+3 more
europepmc +1 more source
Astrocytes as Active Participants in Memory
This review explores how astrocytes support memory by modulating neurotransmitters, interacting with biomolecules, and taking part in synaptic plasticity. We discuss their role across various brain regions and spotlight cutting‐edge methods—such as Ca2+ imaging, optogenetics, chemogenetics, and engram analysis—that have revolutionized our ability to ...
Shay Meron Asher, Inbal Goshen
wiley +1 more source
Paradoxical pattern of haematological risk with clozapine [PDF]
Peter Kenneth Gillman
openalex +1 more source
The pharmacotherapeutic potential of neuropeptide Y for chronic pain
Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley +1 more source