Results 211 to 220 of about 96,379 (348)

Exploring the pathophysiology underlying clozapine‐induced enhancement of glutamatergic transmission through L‐glutamate and D‐serine release associated with pannexin1 hemichannels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4710-4728, October 2025.
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada   +2 more
wiley   +1 more source

Clozapine – a survey of patient perceptions [PDF]

open access: hybrid, 2000
David Taylor   +4 more
openalex   +1 more source

Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour

open access: yesBiological Reviews, Volume 100, Issue 5, Page 1994-2019, October 2025.
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett   +4 more
wiley   +1 more source

Tumor Necrosis Factor Constellation Polymorphism and Clozapine-Induced Agranulocytosis in Two Different Ethnic Groups

open access: bronze, 1997
David Turbay   +6 more
openalex   +1 more source

Astrocytes as Active Participants in Memory

open access: yesJournal of Neurochemistry, Volume 169, Issue 10, October 2025.
This review explores how astrocytes support memory by modulating neurotransmitters, interacting with biomolecules, and taking part in synaptic plasticity. We discuss their role across various brain regions and spotlight cutting‐edge methods—such as Ca2+ imaging, optogenetics, chemogenetics, and engram analysis—that have revolutionized our ability to ...
Shay Meron Asher, Inbal Goshen
wiley   +1 more source

The pharmacotherapeutic potential of neuropeptide Y for chronic pain

open access: yesJournal of Internal Medicine, Volume 298, Issue 4, Page 280-296, October 2025.
Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley   +1 more source

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