Results 241 to 250 of about 61,552 (282)
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Journal of Geriatric Psychiatry and Neurology, 1994
The authors reviewed the use of clozapine in eight patients over age 65 years with treatment-resistant psychoses. Six patients improved. Two patients became more confused. The authors suggest that clozapine be considered in treating elderly psychotic patients, and that its use need not be restricted to schizophrenic patients.
Douglas Kalunian, Frances R. Frankenburg
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The authors reviewed the use of clozapine in eight patients over age 65 years with treatment-resistant psychoses. Six patients improved. Two patients became more confused. The authors suggest that clozapine be considered in treating elderly psychotic patients, and that its use need not be restricted to schizophrenic patients.
Douglas Kalunian, Frances R. Frankenburg
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Journal of Clinical Psychopharmacology, 1997
Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
Martin Kurz +5 more
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Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
Martin Kurz +5 more
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Journal of Clinical Psychopharmacology, 1989
The discovery of clozapine represents such a combination of paradoxes, luck and unfortunate incidents that some people believe the history of clozapine should be entitled "The Clozapine Story" (Stille and Fischer-Cornelssen 1988). One paradox lies in the fact that clozapine is at the same time a very old drug and also one of the newest and most modern ...
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The discovery of clozapine represents such a combination of paradoxes, luck and unfortunate incidents that some people believe the history of clozapine should be entitled "The Clozapine Story" (Stille and Fischer-Cornelssen 1988). One paradox lies in the fact that clozapine is at the same time a very old drug and also one of the newest and most modern ...
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Meta‐analysis examining the epidemiology of clozapine‐associated neutropenia
Acta Psychiatrica Scandinavica, 2018Clozapine is associated with life‐threatening neutropenia. There are no previous meta‐analyses of the epidemiology of clozapine‐associated neutropenia.
N. Myles +10 more
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Psychotherapy and Psychosomatics, 2020
tial for high lethality due to its associated increases in clozapine levels. Moreover, clozapine and pneumonia have strong bidirectional associations, since clozapine may increase the risk of pneumonia [9].
Can-Jun Ruan +4 more
semanticscholar +1 more source
tial for high lethality due to its associated increases in clozapine levels. Moreover, clozapine and pneumonia have strong bidirectional associations, since clozapine may increase the risk of pneumonia [9].
Can-Jun Ruan +4 more
semanticscholar +1 more source
Pharmacopsychiatry, 2008
Clozapine remains one of the most commonly used antipsychotic medications in China. As China has the largest population internationally on clozapine treatment, its experience and research findings are of keen interest to Western psychiatrists. However, most of the related papers have hitherto been published only in Chinese language journals.
Mao Px +6 more
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Clozapine remains one of the most commonly used antipsychotic medications in China. As China has the largest population internationally on clozapine treatment, its experience and research findings are of keen interest to Western psychiatrists. However, most of the related papers have hitherto been published only in Chinese language journals.
Mao Px +6 more
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American Journal of Psychiatry, 1990
Clozapine is a newly released antipsychotic that is associated with a higher prevalence of seizures than traditional neuroleptics. The authors describe four patients who developed seizure activity during clozapine treatment and provide recommendations for clinical management of this problem.
Renée L. Binder, Ellen Haller
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Clozapine is a newly released antipsychotic that is associated with a higher prevalence of seizures than traditional neuroleptics. The authors describe four patients who developed seizure activity during clozapine treatment and provide recommendations for clinical management of this problem.
Renée L. Binder, Ellen Haller
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Optimizing clozapine treatment
Acta Psychiatrica Scandinavica, 2011Clozapine treatment remains the gold standard for treatment-resistant schizophrenia, but treatment with clozapine is associated with several side-effects that complicate the use of the drug. This clinical overview aims to provide psychiatrists with knowledge about how to optimize clozapine treatment.
Jimmi Nielsen +4 more
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Clinical Neuropharmacology, 2015
Clozapine is a major atypical antipsychotic drug used in treatment-resistant schizophrenia (Patel and Allin. Ther Adv Psychopharmacol 2011;1:25-29). It interferes with dopamine binding to D1, D2, D3, and D5 receptors but has high affinity to D4. It also has an anticholinergic effect and antagonizes α-adrenergic, histaminergic, and serotoninergic ...
Alicia Valiente-Gómez +2 more
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Clozapine is a major atypical antipsychotic drug used in treatment-resistant schizophrenia (Patel and Allin. Ther Adv Psychopharmacol 2011;1:25-29). It interferes with dopamine binding to D1, D2, D3, and D5 receptors but has high affinity to D4. It also has an anticholinergic effect and antagonizes α-adrenergic, histaminergic, and serotoninergic ...
Alicia Valiente-Gómez +2 more
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Clozapine—A dangerous drug in a clozapine-naïve subject
Forensic Science International, 2012Clozapine is a uniquely effective antipsychotic, but is very toxic in clozapine-naïve subjects. A 34-year-old male patient in a mental health facility, who was not prescribed clozapine, took 350 mg clozapine obtained from another patient at night. He was found dead the next morning. The presence of cardiomegaly related to obesity may have increased the
Stanworth, D. +2 more
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