Results 91 to 100 of about 1,868,629 (331)
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
The rich-club phenomenon across complex network hierarchies [PDF]
The so-called rich-club phenomenon in a complex network is characterized when nodes of higher degree (hubs) are better connected among themselves than are nodes with smaller degree.
Caetano, Tiberio S.+2 more
core +2 more sources
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
THE ENTOMOLOGICAL CLUB OF THE A. A. A. S [PDF]
n ...
openaire +3 more sources
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Implementation of a Virtual Journal Club in a Clinical Nursing Setting [PDF]
Healthcare practice is increasingly focused on delivering care that is based on published research evidence. Staff development nurses can institute journal clubs to teach nursing staff critical appraisal of research articles and ways to translate ...
Berger, Jill+2 more
core +1 more source