Results 141 to 150 of about 2,008,297 (346)

“Membership Retention in the Fitness Industry: A Qualitative Study and the Development of a Predictive model" [PDF]

open access: yes
The concern over poor membership retention rates in the fitness industry is increasing, yet it has attracted little empirical research. So far, membership retention has mostly been indirectly and narrowly addressed, whereby research has either measured ...
Francis-Smythe, Jan, Watts, Helen
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Four Flats Memorabilia

open access: yes, 1957
Member card for Manila Executives Athletic Club Inc issued to Ron Crecelius.https://digitalcommons.georgefox.edu/fourflats_papers/1060/thumbnail ...
George Fox University Archives
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Clubes social-recreativos: lazer, associativismo e atuação profissional

open access: gold, 2009
André Henrique Chabaribery Capi   +1 more
openalex   +2 more sources

CLUB KIDS

open access: yes, 2017
20. stoljeće kroz svako desetljeće bilo je obilježeno promjenama koje su se najviše očitavale u svijetu mode i glazbe. Od jazz-a i flapper djevojaka u underground barovima 1920-ih u New Yorku do Londonske New Romantics scene 1980-tih ; glazba i moda dva su bitna čimbenika - uz ideologiju i bunt mladih ljudi – za nastanak subkultura ili kontra-kultura ...
openaire   +2 more sources

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