Results 161 to 170 of about 2,008,297 (346)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MANAJEMEN PEMBINAAN PRESTASI PADA KLUB BULUTANGKIS SE-KABUPATEN WONOSOBO TAHUN 2015

open access: yesActive: journal of physical education, sport, health and recreation, 2016
The type of this research is a quantitative with descriptive approach/ survey. Based on result of the research, it know that the founding program in the ABS Club, BST, Indoraya, and Tunas Perkasa have run well.
Septian Williyanto   +1 more
doaj  

Martin's maximum and the non-stationary ideal

open access: yes, 2018
We analyze the non-stationary ideal and the club filter at aleph_1 under ...
Garti, Shimon   +3 more
core  

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Courses de chevaux et courses d’automobiles: les clubs exclusivistes roumains entre la fin du XIXe siècle et le début du XXe siècle

open access: yesTyragetia, 2019
La deuxième moitié du XIXe siècle et le début du XXe siècle voient apparaître en Roumanie des associations sociales, culturels, sportives modernes comme le Jockey Club Roumain [Jockey Club Român] (1875), le Club Royal [Clubul Regal] (1881), l’Automobile ...
Cosmin-Ştefan Dogaru
doaj  

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

The European experience of "Neurology journal club" at the Department of Neurology and Reflexology, Shupyk National Medical Academy of Postgraduate Education

open access: hybrid, 2016
N. Svyrydova   +7 more
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

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