Results 171 to 180 of about 2,207,043 (388)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
, 2017 20. stoljeće kroz svako desetljeće bilo je obilježeno promjenama koje su se najviše očitavale u svijetu mode i glazbe. Od jazz-a i flapper djevojaka u underground barovima 1920-ih u New Yorku do Londonske New Romantics scene 1980-tih ; glazba i moda dva su bitna čimbenika - uz ideologiju i bunt mladih ljudi – za nastanak subkultura ili kontra-kultura ...
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Pteroceraphron Dessart new to the USA (Hymenoptera: Ceraphronoidea)
Biodiversity Data Journal, 2016 István Mikó +2 more
doaj +3 more sources
Values and Governance Systems [PDF]
Cooperative behavior as well as other cultural rules and values are made explicit in organizational units that procure and provide a common service.
Brink, J.R. van den +2 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
MANAJEMEN PEMBINAAN PRESTASI PADA KLUB BULUTANGKIS SE-KABUPATEN WONOSOBO TAHUN 2015
Active: journal of physical education, sport, health and recreation, 2016 The type of this research is a quantitative with descriptive approach/ survey. Based on result of the research, it know that the founding program in the ABS Club, BST, Indoraya, and Tunas Perkasa have run well.
Septian Williyanto +1 more
doaj