Results 51 to 60 of about 308,086 (367)
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
Pagans and Satan and Goths, Oh My: Dark Leisure as Communicative Agency and Communal Identity on the Fringes of the Modern Goth Scene [PDF]
Goth music's cultural terrain has been extensively mapped in the first decade of this century. Through a dark leisure framework, the present article examines the way in which parts of the Goth scene embraced paganism and, latterly, Satanism, as actual ...
Spracklen, B, Spracklen, K
core +1 more source
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu +34 more
wiley +1 more source
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács +9 more
wiley +1 more source
Anecdotally it has been suggested that exposure to some noise sources through leisure activities could have a significant effect on whole-of-life noise exposure.
Warwick Williams, E. Beach, M. Gilliver
semanticscholar +1 more source
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside +11 more
wiley +1 more source
Digital clubbing as a result of metastatic lung cancer [PDF]
Chelsea Roberts, Morteza Khodaee
openalex +1 more source
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
THE BLUE MAN WHO PRESENTED WITH A STROKE [PDF]
A 19-year-old man presented with sudden onset of right eye ptosis, diplopia and giddiness. He had no previous medical illnesses with negative history of exertional dyspnoea, epistaxis, haemoptysis, palpitations, chest pain and chronic cough.
WONG MH, KOH KC
doaj
A rare presentation of Takayasu’s arteritis- unilateral finger clubbing – case report
Background Takayasu’s arteritis (TA) is a granulomatous, large vessel vasculitis with a preponderance for young women. The inflammation results in disruption of the arterial endothelium causing stenosis, endoluminal thrombosis and aneurismal dilatation ...
Shania Niromi Gunasekera +4 more
doaj +1 more source

