Results 41 to 50 of about 129,580 (346)
Frontiers in Neurology, 2021 Moyamoya disease is an idiopathic chronically progressive cerebrovascular disease, which causes both ischemic and hemorrhagic stroke. Genetic studies identified RNF213/Mysterin and GUCY1A3 as disease-causing genes.
Yohei Mineharu, Susumu Miyamoto
doaj +1 more source
A Genome-Wide Analysis Reveals Significant Overlap of Transcription and DNA Repair in Stationary Phase Yeast [PDF]
, 2008 The association between transcription and DNA repair is acknowledged as a player in the generation of mutations in a non-random fashion in prokaryotes and eukaryotes.
Abraham Korol +5 more
core +1 more source
Clues that natural killer cells help to control COVID
Nature, 2021 Natural killer cells can destroy cells infected by SARS-CoV-2, but this immune-system defence malfunctions in people with severe COVID-19. Will this finding drive a search for ways to reinvigorate natural killer cells in such cases? A defence response malfunctions in people with severe COVID-19.
Narni-Mancinelli, Emilie, Vivier, Eric
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
Case Report: Activating PIK3CD Mutation in Patients Presenting With Granulomatosis With Polyangiitis
Frontiers in Immunology, 2021 Activated phosphoinositide 3-kinase δ syndrome (APDS) is an autosomal dominant primary immunodeficiency caused by gain-of-function (GOF) mutations in PIK3CD or PIK3R1 genes.
Meiping Lu +6 more
doaj +1 more source
Clinical, Histological and Trichoscopic Correlations in Scalp Disorders [PDF]
, 2015 Trichoscopy is the term coined for the dermoscopic imaging of scalp and hair. This diagnostic technique, simple and noninvasive, can be used as a handy bedside tool for the diagnosis and follow-up of hair and scalp disorders. It allows the recognition of
Calvieri, Stefano +7 more
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Carnosine inhibits the proliferation of human gastric cancer SGC-7901 cells through both of the mitochondrial respiration and glycolysis pathways. [PDF]
PLoS ONE, 2014 Carnosine, a naturally occurring dipeptide, has been recently demonstrated to possess anti-tumor activity. However, its underlying mechanism is unclear.
Yao Shen +6 more
doaj +1 more source
Dermoscopic Clues of Histopathologically Aggressive Basal Cell Carcinoma Subtypes
Medicina, 2023 Background: The group of histopathologically aggressive BCC subtypes includes morpheaform, micronodular, infiltrative and metatypical BCC. Since these tumors are at increased risk of recurring, micrographically controlled surgery is considered the best therapeutic option.
Elisa Camela +10 more
openaire +4 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source