Results 41 to 50 of about 129,178 (295)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Case Report: Activating PIK3CD Mutation in Patients Presenting With Granulomatosis With Polyangiitis

Frontiers in Immunology, 2021
Activated phosphoinositide 3-kinase δ syndrome (APDS) is an autosomal dominant primary immunodeficiency caused by gain-of-function (GOF) mutations in PIK3CD or PIK3R1 genes.
Meiping Lu, Meiping Lu, Weizhong Gu, Yuanjian Sheng, Jingjing Wang, Xuefeng Xu, Xuefeng Xu   +6 more
doaj   +1 more source

Starve Cancer Cells of Glutamine: Break the Spell or Make a Hungry Monster? [PDF]

, 2019
Distinct from normal differentiated tissues, cancer cells reprogram nutrient uptake and utilization to accommodate their elevated demands for biosynthesis and energy production.
Jiang, Jie, Srivastava, Sankalp, Zhang, Ji   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Dermoscopic Clues of Histopathologically Aggressive Basal Cell Carcinoma Subtypes

Medicina, 2023
Background: The group of histopathologically aggressive BCC subtypes includes morpheaform, micronodular, infiltrative and metatypical BCC. Since these tumors are at increased risk of recurring, micrographically controlled surgery is considered the best therapeutic option.
Elisa Camela, Paula Ilut Anca, Konstantinos Lallas, Chryssoula Papageorgiou, Sofia-Magdalini Manoli, Theodosia Gkentsidi, Polychronia Eftychidou, Konstantinos Liopyris, Dimitrios Sgouros, Zoe Apalla, Aimilios Lallas   +10 more
openaire   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Exhausted and Apoptotic BALF T Cells in Proinflammatory Airway Milieu at Acute Phase of Severe Mycoplasma Pneumoniae Pneumonia in Children

Frontiers in Immunology, 2022
Severe mycoplasma pneumoniae pneumonia (MPP) in children presents with serious clinical complications. Without proper and prompt intervention, it could lead to deadly consequences.
Xi Chen, Fang Liu, Baoying Zheng, Xiaohui Kang, Xiaolin Wang, Wenjun Mou, Hui Zhang, Anxia Jiao, Shunying Zhao, Jingang Gui   +9 more
doaj   +1 more source

Temporal Dynamics of Binocular Disparity Processing with Corticogeniculate Interactions [PDF]

, 1999
A neural model is developed to probe how corticogeniculate feedback may contribute to the dynamics of binocular vision. Feedforward and feedback interactions among retinal, lateral geniculate, and cortical simple and complex cells are used to simulate ...
Grossberg, Stephen, Grunewald, Alexander
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Spontaneous clearance of Chlamydia trachomatis and its associated factors among women attending screening for chlamydia in Shenzhen, China

International Journal of Infectious Diseases
Objectives: This study aimed to investigate the factors associated with the spontaneous clearance of Chlamydia trachomatis, a phenomenon that, despite a growing body of literature, remains understudied in the context of women in China.
Quan Zou, Yu Xie, Li Zhang, Qiuhong Wu, Hailing Ye, Yi Ding, Weiying Chen, Lishan Tian, Jun Yuan, Tao Zhang, Xiaojing Zheng, Weiming Tang, Xiangsheng Chen, Wenjie Dai, Zhenzhou Luo   +14 more
doaj   +1 more source