Results 71 to 80 of about 129,178 (295)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Early B-Cell Differentiation in Merkel Cell Carcinomas: Clues to Cellular Ancestry [PDF]
Cancer Research, 2013 AbstractMerkel cell carcinoma (MCC) is a highly malignant neuroendocrine nonmelanoma skin cancer, which is associated with the Merkel cell polyoma virus (MCPyV). Recently, expression of the terminal deoxynucleotidyl transferase (TdT) and the paired box gene 5 (PAX 5) has been consistently reported in the majority of MCCs.
zur Hausen, Axel +4 more
openaire +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Case Reports in Pathology, 2015 Pseudomalignant erosion is a diagnostic pitfall for pathologists in the differential diagnosis of malignant neoplasms. Here, we present a challenging case of a biopsy specimen from the eroded head of a polyp at the esophagogastric junction.
Takahiko Nakajima +9 more
doaj +1 more source
Indian Journal of Medical and Paediatric Oncology, 2013 Paraneoplastic pemphigus (PNP) is often a fatal autoimmune bullous disease characterized by severe stomatitis, polymorphous skin eruptions, and underlying neoplasms. We describe a patient with PNP associated with follicular dendritic cell sarcoma (FDCS),
Saphalta Baghmar +3 more
doaj +1 more source
Texture Segregation, Surface Representation, and Figure-ground Separation [PDF]
, 1996 A widespread view is that most of texture segregation can be accounted for by differences in the spatial frequency content of texture regions. Evidence from both psychophysical and physiological studies indicate, however, that beyond these early ...
Grossberg, Stephen, Pessoa, Luiz
core +1 more source
Clinical, Histological and Trichoscopic Correlations in Scalp Disorders [PDF]
, 2015 Trichoscopy is the term coined for the dermoscopic imaging of scalp and hair. This diagnostic technique, simple and noninvasive, can be used as a handy bedside tool for the diagnosis and follow-up of hair and scalp disorders. It allows the recognition of
Calvieri, Stefano +7 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules
Gynecology Obstetrics & Reproductive Medicine, 2013 Lactobacilli are member of normal vaginal flora. They maintain low pH of vaginal discharge by metabolising glycogen in vaginal epithelial cell and protects the vagina against the pathogenic microorganisms.
Şayeste Demirezen +2 more
doaj
Annular papulovesicular lesions with a purpuric center in a female inpatient
Clinical Case ReportsKey Clinical Message Epidermal multinucleated keratinocytes, or epidermal grape cells, in the absence of any viral infection, are an important histological finding and a clue for the diagnosis of dermatoses induced by external irritation or aggression ...
David Alvarez Martinez +2 more
doaj +1 more source