Results 191 to 200 of about 11,335 (270)

Correlation Between Gut Microbiota, Metabolites, and Diabetic Complications: A Two‐Sample Mendelian Randomization Study

open access: yesMedicine Advances, EarlyView.
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang   +6 more
wiley   +1 more source

Neuroprotective Effects of RNS60 in TDP‐43 Pathology‐Associated Amyotrophic Lateral Sclerosis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction TDP‐43 pathology is broadly observed in the cerebral cortex of patients with amyotrophic lateral sclerosis (ALS). RNS60, an experimental treatment for acute ischemic stroke and ALS, enhanced mitochondrial biogenesis and function in other preclinical models.
Danny R. Vesevick   +4 more
wiley   +1 more source

A transient protoplast expression system for functional gene validation in sugarcane: Focus on drought response and immune pathways

open access: yesNew Plant Protection, EarlyView.
We developed a transient expression system for sugarcane using Guitang 42 culm, suitable for various assays such as GCaMP6‐based calcium imaging. This system revealed that ScNCED3 acts as an early drought response signal, positively regulated by ScPYL4‐12, ScOST1‐12, and ScMPK6‐11.
Dianqi Wu   +10 more
wiley   +1 more source

Irreversible Electroporation for Tonsillar Ablation in Adults

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the safety and efficacy of irreversible electroporation for non‐thermal ablation of tonsils in adults. Study Design Prospective interventional case series of 24 adult patients referred for tonsillectomy that were followed for 3 months. Setting Academic medical center.
Codrut Sarafoleanu   +4 more
wiley   +1 more source

Inequalities in intraspecific plant–lemur interactions drive seed dispersal patterns

open access: yesOikos, EarlyView.
Biotic interactions occur between individuals and accumulate to shape species‐level interaction structure across a community. Skewed interaction structures, where a few individuals are highly connected and most have few interactions, are increasingly identified at the individual‐level.
Jadelys Tonos   +2 more
wiley   +1 more source

Differential performance of polygenic risk scores for heart disease in Hispanic/Latino subgroups: Findings of the Hispanic Community Health Study/Study of Latinos. [PDF]

open access: yesHGG Adv
Hutten CG   +12 more
europepmc   +1 more source

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