Results 1 to 10 of about 175,275 (300)

A pragmatic cluster randomised trial evaluating three implementation interventions [PDF]

Implementation Science, 2012
Background Implementation research is concerned with bridging the gap between evidence and practice through the study of methods to promote the uptake of research into routine practice.
Rycroft-Malone Jo, Seers Kate, Crichton Nicola, Chandler Jackie, Hawkes Claire A, Allen Claire, Bullock Ian, Strunin Leo   +7 more
doaj   +7 more sources

Extending a parallel cluster randomised trial into a stepped-wedge cluster randomised trial: implications for interpretation. [PDF]

BMJ Glob Health
Hemming K, Taljaard M.
europepmc   +4 more sources

Cluster randomised trials in the medical literature: two bibliometric surveys [PDF]

BMC Medical Research Methodology, 2004
Background Several reviews of published cluster randomised trials have reported that about half did not take clustering into account in the analysis, which was thus incorrect and potentially misleading.
Bland J Martin
doaj   +6 more sources

Feasibility of a cluster randomised trial on the effect of trauma life support training: a pilot study in India. [PDF]

BMJ Open
Objective To assess the feasibility of conducting a cluster randomised controlled trial comparing the effects of Advanced Trauma Life Support (ATLS) and Primary Trauma Care (PTC) with standard care on patient outcomes.Design This was a pilot pragmatic ...
Gerdin Wärnberg M, Basak D, Berg J, Chatterjee S, Felländer-Tsai L, Ghag G, Juillard C, Khajanchi M, Khan T, Mishra A, Nandu VV, Roy N, Singh R, Soni KD, Strömmer L.   +14 more
europepmc   +2 more sources

Enhancing Recruitment Using Teleconference and Commitment Contract (ERUTECC): a stepped wedge cluster randomised trial within the EFFECTS trial. [PDF]

Ups J Med Sci
Background: Two out of three randomised controlled trials (RCTs) fail to meet their recruitment goals. Recruitment to Efficacy oF Fluoxetine – a randomisEd Controlled Trial in Stroke (EFFECTS), fluoxetine for stroke recovery was slower than anticipated ...
Isaksson E, Näsman P, Wester P, Laska AC, Lundström E.   +4 more
europepmc   +2 more sources

Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy

Trials, 2023
Background Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic.
Mary L. Venn, Charles H. Knowles, Elizabeth Li, James Glasbey, Dion G. Morton, Richard Hooper, ESCP EAGLE Safe Anastomosis Collaborative   +6 more
doaj   +1 more source

Registry randomised trials: a methodological perspective

BMJ Open, 2023
Registry randomised clinical trials (RRCTs) have the potential to provide pragmatic answers to important clinical questions. RRCTs can be embedded into large population-based registries or smaller single site registries to provide timely answers at a ...
Christopher M Reid, Susannah Ahern, Ian Harris, Steven Y C Tong, Angela L Brennan, Dorota A Doherty, Carol Hodgson, Stephen McDonald, Jennifer Reilly, Jane Shrapnel, Charmaine S Tam, Leonie Wilcox, Anitha Balagurunathan, Belinda E Butcher   +13 more
doaj   +1 more source

A study protocol for a cluster-randomised controlled trial of smartphone-activated first responders with ultraportable defibrillators in out-of-hospital cardiac arrest: The First Responder Shock Trial (FIRST)

Resuscitation Plus, 2023
Objective: To describe the First Responder Shock Trial (FIRST), which aims to determine whether equipping frequently responding, smartphone-activated (GoodSAM) first responders with an ultraportable AED can increase 30-day survival rates in OHCA. Methods:
Verity Todd, Bridget Dicker, Daniel Okyere, Karen Smith, Tony Smith, Graham Howie, Dion Stub, Michael Ray, Ralph Stewart, Tony Scott, Andy Swain, Natalie Heriot, Aroha Brett, Emily Mahony, Ziad Nehme   +14 more
doaj   +1 more source

Contamination in complex healthcare trials:the falls in care homes (FinCH) study experience [PDF]

, 2020
BACKGROUND: Trials are at risk of contamination bias which can occur when participants in the control group are inadvertently exposed to the intervention.
Allen, F, Darby, J, Fox, C, Gordon, A L, Horne, J C, Leighton, P, Logan, P A, Robinson, K, Sims, Erika   +8 more
core   +1 more source

Baseline testing in cluster randomised controlled trials: should this be done?

BMC Medical Research Methodology, 2019
Background Comparisons of baseline covariates in randomised controlled trials whilst often undertaken is regarded by many as an exercise in futility.
Jaime E. Bolzern, Alex Mitchell, David J. Torgerson   +2 more
doaj   +1 more source