Methodological bias in cluster randomised trials [PDF]
BMC Medical Research Methodology, 2005 Abstract Background Cluster randomised trials can be susceptible to a range of methodological problems. These problems are not commonly recognised by many researchers. In this paper we discuss the issues that can lead to bias in cluster trials. Methods
Hahn, Seokyung +3 more
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How to design efficient cluster randomised trials [PDF]
BMJ, 2017 Cluster randomised trials have diminishing returns in power and precision as cluster size increases. Making the cluster a lot larger while keeping the number of clusters fixed might yield only a very small increase in power and precision, owing to the intracluster correlation.
Hemming, K +4 more
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Baseline testing in cluster randomised controlled trials: should this be done?
BMC Medical Research Methodology, 2019 Background Comparisons of baseline covariates in randomised controlled trials whilst often undertaken is regarded by many as an exercise in futility.
Jaime E. Bolzern +2 more
doaj +1 more source
Exploring demographic and lifestyle associations with patient experience following telephone triage by a primary care doctor or nurse:secondary analyses from a cluster randomised controlled trial [PDF]
, 2015 The ESTEEM trial was a cluster randomised controlled trial that compared two telephone triage management systems (general practitioner (GP) or a nurse supported by computer decision support software) with usual care, in response to a request for same-day
Bunn +18 more
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British medical journal, 2022 Objectives To evaluate the effectiveness of an intervention, with and without a height adjustable desk, on daily sitting time, and to investigate the relative effectiveness of the two interventions, and the effectiveness of both interventions on physical
C. Edwardson +15 more
semanticscholar +1 more source
Trials, 2018 Background Many randomised controlled trials (RCTs) fail to meet their recruitment goals in time. Trialists are advised to include study recruitment strategies within their trials. EFFECTS is a Swedish, academic-led RCT of fluoxetine for stroke recovery.
Erik Lundström +4 more
doaj +1 more source
Resuscitation Plus, 2022 Aims: The Prehospital Optimal Shock Energy for Defibrillation (POSED) study will assess the feasibility of conducting a cluster randomised controlled study of clinical effectiveness in UK ambulance services to identify the optimal shock energy for ...
Helen Pocock +9 more
doaj +1 more source
Evidence for risk of bias in cluster randomised trials: review of recent trials published in three general medical journals [PDF]
, 2003 Objective To examine the prevalence of a risk of bias associated with the design and conduct of cluster randomised controlled trials among a sample of recently published studies.
Puffer, S, Torgerson, D J, Watson, J
core +2 more sources
The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting
British medical journal, 2015 The stepped wedge cluster randomised trial is a novel research study design that is increasingly being used in the evaluation of service delivery type interventions.
K. Hemming +4 more
semanticscholar +1 more source
Health facility utilisation changes during the introduction of community case management of malaria in South Western Uganda: An interrupted time series approach. [PDF]
, 2015 This dataset contains all visits made to health facilities in Bwambara Sub-county, South Western Uganda as part of a cluster randomised trial.
Alexander, Neal +7 more
core +7 more sources