Exploratory cluster analysis of self-reported adverse events associated with antidepressants using Gower distance and partitioning around medoids: a single-center cross-sectional study. [PDF]
Zhai Q +5 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Natural Frequency Analysis of Cluster Dither with Partially Tapered Spokes for Three-Axis Ring Laser Gyroscopes. [PDF]
Kim CJ, An JE, Yu H, Park J.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Determinants and typologies of health system resilience: A data-driven framework for prioritising investment. [PDF]
Balinia Adda R, Pwayirane C.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Species delimitation and taxonomic revision of the <i>Rhamnella franguloides</i> complex (Rhamnaceae). [PDF]
An Q, Lu Z, Zhou X.
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Glycoproteomic Signatures of IgG Subclass <i>N</i>-Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies. [PDF]
Wu T +9 more
europepmc +1 more source

