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CLUSTER ANALYSIS IN BIOTECHNOLOGY [PDF]

open access: yesBiotechnologia Acta, 2017
Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, Kyiv The goal of publication was the analysis of cluster methods and possibility of their application in biotechnology.
O. M. Klyuchko
doaj   +4 more sources

Understanding doxorubicin associated calcium remodeling during triple-negative breast cancer treatment: an in silico study

open access: yesExploration of Targeted Anti-tumor Therapy, 2021
Aim: Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with high heterogeneity, rapid progression, and paucity of treatment options. The most effective chemotherapeutic drug used to treat TNBC is doxorubicin (Doxo) which
Garhima Arora   +2 more
doaj   +1 more source

Exploring gene knockout strategies to identify potential drug targets using genome-scale metabolic models

open access: yesScientific Reports, 2021
Research on new cancer drugs is performed either through gene knockout studies or phenotypic screening of drugs in cancer cell-lines. Both of these approaches are costly and time-consuming.
Abhijit Paul   +5 more
doaj   +1 more source

Coral endosymbiont growth is enhanced by metabolic interactions with bacteria

open access: yesNature Communications, 2023
Bacteria are key contributors to microalgae resource acquisition, competitive performance, and functional diversity, but their potential metabolic interactions with coral microalgal endosymbionts (Symbiodiniaceae) have been largely overlooked.
Jennifer L. Matthews   +10 more
doaj   +1 more source

To cluster, or not to cluster: An analysis of clusterability methods [PDF]

open access: yesPattern Recognition, 2019
Clustering is an essential data mining tool that aims to discover inherent cluster structure in data. For most applications, applying clustering is only appropriate when cluster structure is present. As such, the study of clusterability, which evaluates whether data possesses such structure, is an integral part of cluster analysis. However, methods for
Andreas Adolfsson   +2 more
openaire   +3 more sources

Coming home to die? The association between migration and mortality in rural Tanzania before and after ART scale-up [PDF]

open access: yesGlobal Health Action, 2014
Background: Prior to the scale-up of antiretroviral therapy (ART), demographic surveillance cohort studies showed higher mortality among migrants than residents in many rural areas.
Francis Levira   +2 more
doaj   +1 more source

Population density and energy consumption: A study in Indonesian provinces

open access: yesHeliyon, 2022
As the world’s fourth most populous country, the population growth rate in Indonesia is expected to stay high. Owing to a combination of high-speed urbanization and increasing population density, economic growth is predicted to increase the demand for ...
Irfani Fithria Ummul Muzayanah   +4 more
doaj   +1 more source

Cluster Correspondence Analysis [PDF]

open access: yesPsychometrika, 2017
A method is proposed that combines dimension reduction and cluster analysis for categorical data by simultaneously assigning individuals to clusters and optimal scaling values to categories in such a way that a single between variance maximization objective is achieved.
van de Velden, M.   +2 more
openaire   +5 more sources

Detection and analysis of cluster–cluster filaments [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2020
ABSTRACTIn this work, we identify and analyse the properties of cluster–cluster filaments within a cosmological simulation assuming that they are structures connecting maxima of the density field defined by dark matter haloes with masses $M \, \ge 10^{14}\, h^{-1} \, \mathrm{M_{\odot }}$.
Federico Stasyszyn   +8 more
openaire   +4 more sources

Targeted protein degradation by Trim-Away using cell resealing coupled with microscopic image-based quantitative analysis

open access: yesFrontiers in Cell and Developmental Biology, 2022
“Trim-Away” technology enables rapid degradation of endogenous proteins without prior modification of protein-coding genes or mRNAs through delivery of antibodies that target proteins of interest.
Rina Kunishige   +6 more
doaj   +1 more source

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