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Understanding doxorubicin associated calcium remodeling during triple-negative breast cancer treatment: an in silico study

open access: yesExploration of Targeted Anti-tumor Therapy, 2021
Aim: Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with high heterogeneity, rapid progression, and paucity of treatment options. The most effective chemotherapeutic drug used to treat TNBC is doxorubicin (Doxo) which
Garhima Arora   +2 more
doaj   +1 more source

Exploring gene knockout strategies to identify potential drug targets using genome-scale metabolic models

open access: yesScientific Reports, 2021
Research on new cancer drugs is performed either through gene knockout studies or phenotypic screening of drugs in cancer cell-lines. Both of these approaches are costly and time-consuming.
Abhijit Paul   +5 more
doaj   +1 more source

Coral endosymbiont growth is enhanced by metabolic interactions with bacteria

open access: yesNature Communications, 2023
Bacteria are key contributors to microalgae resource acquisition, competitive performance, and functional diversity, but their potential metabolic interactions with coral microalgal endosymbionts (Symbiodiniaceae) have been largely overlooked.
Jennifer L. Matthews   +10 more
doaj   +1 more source

Population density and energy consumption: A study in Indonesian provinces

open access: yesHeliyon, 2022
As the world’s fourth most populous country, the population growth rate in Indonesia is expected to stay high. Owing to a combination of high-speed urbanization and increasing population density, economic growth is predicted to increase the demand for ...
Irfani Fithria Ummul Muzayanah   +4 more
doaj   +1 more source

Coming home to die? The association between migration and mortality in rural Tanzania before and after ART scale-up [PDF]

open access: yesGlobal Health Action, 2014
Background: Prior to the scale-up of antiretroviral therapy (ART), demographic surveillance cohort studies showed higher mortality among migrants than residents in many rural areas.
Francis Levira   +2 more
doaj   +1 more source

Targeted protein degradation by Trim-Away using cell resealing coupled with microscopic image-based quantitative analysis

open access: yesFrontiers in Cell and Developmental Biology, 2022
“Trim-Away” technology enables rapid degradation of endogenous proteins without prior modification of protein-coding genes or mRNAs through delivery of antibodies that target proteins of interest.
Rina Kunishige   +6 more
doaj   +1 more source

Comparing the impacts of fossil and renewable energy investments in Indonesia: A simple general equilibrium analysis

open access: yesHeliyon, 2020
Increasing electricity capacity to support economic growth has become a national development priority in Indonesia. The construction of a power plant needs to consider not only economic but also social and environmental impacts because the government can
Djoni Hartono   +5 more
doaj   +1 more source

Image Processing Filters for Grids of Cells Analogous to Filters Processing Grids of Pixels

open access: yesFrontiers in Computer Science, 2021
Intra- and extra-cellular processes shape tissues together. For understanding how neighborhood relationships between cells play a role in this process, having image processing filters based on these relationships would be beneficial. Those operations are
Robert Haase , Robert Haase 
doaj   +1 more source

Influence of Socioeconomic, Demographics, and Prices Factors on Cooking Fuel Choice of Indonesian Households

open access: yesJurnal Economia, 2023
There are differences in the choice of cooking fuel in Indonesian households. Some households still not yet used clean fuel for daily cooking, even though clean energy is crucial and included in the Sustainable Development Goals (SDGs).
Hadi Prasojo, Djoni Hartono
doaj   +1 more source

Cluster Analysis of Ranunculus Species [PDF]

open access: yes, 2002
The aim of the experiment was to examine whether the morphological characters of eleven species of Ranunculus collected from a number of populations were in agreement with the genetic data (isozyme).
SURANTO,
core   +2 more sources

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