Results 191 to 200 of about 27,554,683 (360)

Sequencing and Transcriptional Analysis of the Biosynthesis Gene Cluster of Putrescine-Producing Lactococcus lactis

, 2011
Víctor Ladero, Fergal P. Rattray, Baltasar Mayo, M. Cruz Martín, Marı́a Fernández, Miguel A. Álvarez   +5 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A cluster analysis of operating room nurses' profiles based on their clinical decision-making for pressure injury prevention. [PDF]

Front Public Health
Guo ZS, Wang XM, Fan HL, Wei L, Zhang X, Guo Y, Niu YB, Li YJ.   +7 more
europepmc   +1 more source

Image 4_An unsupervised cluster analysis of multimorbidity patterns in older adults in Shenzhen, China.jpeg

Xiaolong Guo (582898), Peiyi Liu (4262206), Jing Guo (102972), Naiwen Zhang (6417992), Haiyan Huang (3900), Jianjun Liu (28194), Zhen Tan (384977), Guo Dan (7445327)   +7 more
openalex   +1 more source

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers.

Journal of Allergy and Clinical Immunology, 2016
P. Tomassen, G. Vandeplas, T. Van Zele, L. Cardell, Julia Arebro, H. Olze, U. Förster‐Ruhrmann, M. Kowalski, A. Olszewska-Ziąber, G. Holtappels, N. De Ruyck, Xiangdong Wang, C. V. van Drunen, J. Mullol, P. Hellings, V. Hox, E. Toskala, G. Scadding, V. Lund, Luo Zhang, W. Fokkens, C. Bachert   +21 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Data-driven frailty and reserve phenotypes in older outpatients: a cluster analysis of complementary geriatric assessment. [PDF]

Front Aging
Belfiori M, Salis F, Puxeddu B, Mulas M, Puligheddu M, Mandas A.   +5 more
europepmc   +1 more source

Comparative analysis of WN and PM methodologies: Figure (a) displays the bar chart comparing WN and PM across five distinct concept sets (Methods), highlighting the number of concept sets where the cluster mean distance is significantly lower, indicative of superior embeddings.

Enock Niyonkuru (21246879), Mauricio Soto Gomez (21246882), Elena Casarighi (13205074), Stephan Antogiovanni (21246885), Hannah Blau (6206984), Justin T. Reese (12547269), Giorgio Valentini (45586), Peter N. Robinson (7814636)   +7 more
openalex   +1 more source