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Orphanet Journal of Rare Diseases, 2008 Cluster headache (CH) is a primary headache disease characterized by recurrent short-lasting attacks (15 to 180 minutes) of excruciating unilateral periorbital pain accompanied by ipsilateral autonomic signs (lacrimation, nasal congestion, ptosis, miosis,
Ducros Anne, Leroux Elizabeth
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Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan
The Journal of Headache and Pain, 2022 Background Cluster headache is a highly debilitating neurological disorder with considerable inter-ethnic differences. Genome-wide association studies (GWAS) recently identified replicable genomic loci for cluster headache in Europeans, but the genetic ...
Shih-Pin Chen +14 more
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Annals of Indian Academy of Neurology, 2018 Cluster headache (CH) is a debilitating primary headache disorder. Although uncommon, affecting only 0.1% of population, it is one of the most painful conditions known to humankind.
William S Kingston, David W Dodick
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The Journal of Headache and Pain, 2023 Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown
Caroline Ran +6 more
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The Journal of Headache and Pain, 2023 Background Cluster headache is a severe and disabling primary headache disorder. Galcanezumab is a monoclonal antibody against calcitonin gene-related peptide and a preventive therapy for episodic cluster headache.
Yooha Hong +4 more
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Cluster Headache in a Case of Ophthalmic Cysticercosis [PDF]
Journal of Clinical and Diagnostic Research, 2019 Cluster headache is considered to be a primary headache. A lot of literature has been published for apparent cluster headache like conditions arising out of organic pathologies like tumours, dissection and infection in the craniofacial area although the ...
Animesh Das, Robin Bansal
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Phase dependent hypothalamic activation following trigeminal input in cluster headache
The Journal of Headache and Pain, 2020 Background Task-free imaging approaches using PET have shown the posterior hypothalamus to be specifically activated during but not outside cluster headache attacks. Evidence from task related functional imaging approaches however is scarce.
Laura H. Schulte +2 more
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Cluster headache and kynurenines
The Journal of Headache and Pain, 2023 Background The glutamatergic neurotransmission has important role in the pathomechanism of primary headache disorders. The kynurenine metabolites derived from catabolism of tryptophan (Trp) have significant involvement not only in glutamatergic processes,
Bernadett Tuka +8 more
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Cephalalgia Reports, 2022 Objective: To summarise the history of cluster headache evolving concepts and growing insights. Background: Excruciating pain, activation of the parasympathetic nervous system, and circadian rhythmicity characterise cluster headache attacks.
Heiko Pohl
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Exploring the Connection Between Sleep and Cluster Headache: A Narrative Review
Pain and Therapy, 2020 Cluster headache is a rare form of headache associated with sleep and even speculated to be a manifestation of a sleep disorder rather than a primary headache. Cluster headache exhibits both circadian and circannual rhythmicity. While attacks often occur
Joseph V. Pergolizzi +5 more
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