Results 31 to 40 of about 9,834 (312)

The First Review Conference of the Convention on Cluster Munitions (2015) [PDF]

, 2015
As agreed at the 5MSP, the First Review Conference of the CCM took place in Dubrovnik, Croatia, from 7 to 11 September ...
Munitions, Convention on Cluster
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Effects of interior ballistic factors on dispersion of central blast tube cluster munitions

Journal of Measurement Science and Instrumentation, 2015
This article uses nonlinear dynamics analysis software AUTODYN-2Dto establish an interior ballistic model of central blast tube cluster munitions dispersion.The interior ballistic process of the central blast tube cluster munitions dispersion was ...
YUAN Li-dong, WANG Zhi-jun, WU Guo-dong
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Multiloitering Munition Cooperative Surrounding and Attack Method Based on Wolf Pack Algorithm

International Journal of Aerospace Engineering
Aiming at the optimization problem of multiloitering munitions cooperatively surrounding moving targets, this paper proposes a cooperative surrounding and attack method based on the wolf pack algorithm (WPA).
Zetian Zhang, Min Gao, Dan Fang, Chaowang Li   +3 more
doaj   +1 more source

Dissecting the Debate on Cluster Munitions

, 2023
Völkerrechtsblog
openaire   +1 more source

The Fifth Meeting of States Parties to the Convention on Cluster Munitions (2014) [PDF]

, 2014
On 2 September 2014, the Fifth Meeting of States Parties was opened by the Permanent Representative of Zambia to the United Nations Office and other international organizations in Geneva, Encyla Sinjela, on behalf of the Minister for Foreign Affairs of ...
Munitions, Convention on Cluster
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

International law-making and the Geneva Declaration on Human Rights at Sea

Leiden Journal of International Law
The Geneva Declaration on Human Rights at Sea is a recent initiative of the non-governmental organization (NGO), Human Rights at Sea, and provides an opportunity to examine how an NGO-led initiative may contribute to international law-making.
Natalie Klein
doaj   +1 more source