Group sequential designs for stepped-wedge cluster randomised trials. [PDF]
BACKGROUND/AIMS: The stepped-wedge cluster randomised trial design has received substantial attention in recent years. Although various extensions to the original design have been proposed, no guidance is available on the design of stepped-wedge cluster ...
Grayling, Michael J +2 more
core +5 more sources
Cluster randomised trials [PDF]
Although randomised controlled trials are the reference methodology to assess the effects of therapeutic interventions, for interventions that naturally occur in groups of individuals random allocation of participants may be inappropriate. In these cases, the unit of random allocation may be the group or cluster, rather than the individual.
BARBUI, Corrado, CIPRIANI, Andrea
openaire +4 more sources
Methodological bias in cluster randomised trials [PDF]
Abstract Background Cluster randomised trials can be susceptible to a range of methodological problems. These problems are not commonly recognised by many researchers. In this paper we discuss the issues that can lead to bias in cluster trials. Methods
Hahn, Seokyung +3 more
openaire +5 more sources
How to design efficient cluster randomised trials [PDF]
Cluster randomised trials have diminishing returns in power and precision as cluster size increases. Making the cluster a lot larger while keeping the number of clusters fixed might yield only a very small increase in power and precision, owing to the intracluster correlation.
Hemming, K +4 more
openaire +3 more sources
Exploring demographic and lifestyle associations with patient experience following telephone triage by a primary care doctor or nurse:secondary analyses from a cluster randomised controlled trial [PDF]
The ESTEEM trial was a cluster randomised controlled trial that compared two telephone triage management systems (general practitioner (GP) or a nurse supported by computer decision support software) with usual care, in response to a request for same-day
Bunn +18 more
core +2 more sources
Background Many randomised controlled trials (RCTs) fail to meet their recruitment goals in time. Trialists are advised to include study recruitment strategies within their trials. EFFECTS is a Swedish, academic-led RCT of fluoxetine for stroke recovery.
Erik Lundström +4 more
doaj +1 more source
Aims: The Prehospital Optimal Shock Energy for Defibrillation (POSED) study will assess the feasibility of conducting a cluster randomised controlled study of clinical effectiveness in UK ambulance services to identify the optimal shock energy for ...
Helen Pocock +9 more
doaj +1 more source
Friendship Bench trial: lay worker training in problem-solving therapy to reduce symptoms of common mental disorders [PDF]
The Friendship Bench trial is a cluster-randomised trial of the effect of problem-solving therapy training for lay workers on symptoms of common mental disorders among clinic attenders in Harare, Zimbabwe. This dataset enables replication of analysis for
Abas, Melanie +13 more
core +1 more source
Analysis of a trial randomised in clusters [PDF]
A cluster randomised study is one where a group of subjects are randomised to the same treatment together—for example, when women in some districts are offered breast cancer screening and compared with women in other districts, or when the patients of general practitioners who have been given special training are compared with the patients of those who
S M, Kerry, J M, Bland
openaire +2 more sources
Health facility utilisation changes during the introduction of community case management of malaria in South Western Uganda: An interrupted time series approach. [PDF]
This dataset contains all visits made to health facilities in Bwambara Sub-county, South Western Uganda as part of a cluster randomised trial.
Alexander, Neal +7 more
core +7 more sources

