Results 51 to 60 of about 175,275 (302)

The current use of feasibility studies in the assessment of feasibility for stepped-wedge cluster randomised trials: a systematic review

BMC Medical Research Methodology, 2019
Background Stepped-wedge cluster randomised trials (SW-CRTs) are a pragmatic trial design, providing an unprecedented opportunity to increase the robustness of evidence underpinning implementation and quality improvement interventions.
Caroline A. Kristunas, Karla Hemming, Helen Eborall, Sandra Eldridge, Laura J. Gray   +4 more
doaj   +1 more source

Effects of post-abortion family planning services on contraceptive practices in China : protocol for a clustered randomized controlled trial [PDF]

, 2017
Study objectives: To determine whether integrating post-abortion services in hospital settings in China will increase the contraceptive use and decrease repeat abortion rates. Study design: Three-arms cluster randomised controlled trial in which the unit
Li, Jiong, Olsen, Jørn, Temmerman, Marleen, Wang, Shuchen, Zhang, Wei Hong   +4 more
core   +1 more source

A website for cluster randomised trials including stepped wedge: facilitating quality trials and methodological research

Trials
Background A cluster randomised trial is a randomised controlled trial in which groups of individuals (clusters) are randomised to treatment arms.
Claire L. Chan, Clémence Leyrat, James Martin, Jennifer Thompson, Elizabeth L. Turner, Sandra M. Eldridge   +5 more
doaj   +1 more source

Protocol for a Cluster Randomised Controlled Trial to Compare the “Taste & See” Programme—A Church-Based Programme to Develop a Healthy Relationship with Food—With a Wait-List Control

Religions, 2018
(1) Background: Obesity is strongly associated with poor mental-health. Spiritual and religious wellbeing is associated with improved mental well-being and reduced emotional eating.
Deborah Lycett
doaj   +1 more source

Sample size in cluster randomised trials with unequal clusters [PDF]

Trials, 2011
Objectives The aim of RCTs is to obtain unbiased estimates of treatment effects to answer the question of interest. In a cluster randomised trial (CRT), maximum statistical efficiency is obtained if an equal sized sample from each cluster is selected. In practice, the ability to achieve equal cluster size is an exception rather than the norm.
Holloway Ivana, Farrin Amanda
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Assessment of vaccine herd protection in a cluster-randomised trial of Vi conjugate vaccine against typhoid fever: results of further analysisResearch in context

EClinicalMedicine, 2023
Summary: Background: A cluster-randomised trial of Vi-tetanus toxoid (Vi-TT) conjugate vaccine conducted in urban Bangladeshi children found a high level of direct protection by Vi-TT but no significant vaccine herd protection.
Farhana Khanam, Deok Ryun Kim, Xinxue Liu, Merryn Voysey, Virginia E. Pitzer, K. Zaman, Andrew J. Pollard, Firdausi Qadri, John D. Clemens   +8 more
doaj   +1 more source

Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT) : Study protocol for a cluster randomised control trial [PDF]

, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Boote, Jonathan, Bradburn, Mike J., Cooper, Cindy L., Davis, Sarah, Elphick, Heather, Horspool, Michelle J., Julious, Steven A., Norman, Paul, Smithson, W. H., vanStaa, Tjeerd   +9 more
core   +4 more sources

Community involvement in dengue vector control: cluster randomised trial [PDF]

BMJ, 2009
To assess the effectiveness of an integrated community based environmental management strategy to control Aedes aegypti, the vector of dengue, compared with a routine strategy. Design Cluster randomised trial. Setting Guantanamo, Cuba. Participants 32 circumscriptions (around 2000 inhabitants each).
Vanlerberghe, V., Toledo, M. E., Rodríguez, M., Gomez, D., Baly, A., Benitez, J. R., Van der Stuyft, P.   +6 more
openaire   +6 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source