Results 41 to 50 of about 415,792 (296)

Precision of Design Effect in Cluster Sampling [PDF]

The Egyptian Statistical Journal, 1993
A simulation study is performed to examine the precision of design effect in single-stage and two-stage cluster sampling without stratification and equal cluster sizes. Interest is focused on the effect on precision of such factors as sample size, number
M. Y. Radwan, Z.A. El-Beshir
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Measuring Access and Practice: Designing a Survey Methodology for the Hygiene, Sanitation and Water Sector [PDF]

Access to safe water and sanitary means of excreta disposal are essential elements of human development and poverty alleviation. It is estimated that one in four people in the developing world lacks access to water while over half the population has ...
Bostoen, Kristof
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Estudo de base populacional sobre as condições periodontais e determinantes socioeconômicos em adultos residentes no município de Guarulhos (SP), Brasil, 2006 Population based study on periodontal conditions and socioeconomic determinants in adults in the city of Guarulhos (SP), Brazil, 2006

Revista Brasileira de Epidemiologia, 2011
OBJETIVO: Este estudo descreveu a prevalência de condições periodontais e sua associação com variáveis demográficas, socioeconômicas e comportamentais em adultos de 35 a 44 anos residentes no município de Guarulhos, São Paulo, 2006.
Antônio Carlos Frias, José Leopoldo Ferreira Antunes, Maristela Vilas Boas Fratucci, Celso Zilbovicius, Simone Rennó Junqueira, Silvia Ferreira de Souza, Érika Miti Yassui   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Evaluation of Three Sampling Methods to Monitor Outcomes of Antiretroviral Treatment Programmes in Low- and Middle-Income Countries.

, 2010
BACKGROUND: Retention of patients on antiretroviral therapy (ART) over time is a proxy for quality of care and an outcome indicator to monitor ART programs. Using existing databases (Antiretroviral in Lower Income Countries of the International Databases
ART Linc of IeDEA and MSF Collaborations, Yves Souteyrand, Poulet, E, Mahy, M, Bennett Diane, Tassie, Jean-Michel, Mary Mahy, Harries, Anthony, Pujades-Rodríguez, M, François Dabis, Schechter Mauro, Mauro Schechter, Harries Anthony, Anthony Harries, Schechter, M, Karen Malateste, Dabis François, Tassie Jean-Michel, Dabis, F, Malateste, K, Bennett, D, Malateste, Karen, Harries, A D, Bennett, Diane, Mahy Mary, Diane Bennett, Schechter, Mauro, Tassie, J-M, Tassie, JM, Jean-Michel Tassie, Pujades-Rodríguez Mar, Poulet Elisabeth, Malateste Karen, Poulet, Elisabeth, Mar Pujades-Rodríguez, Souteyrand, Y, null null, Dabis, François, Pujades-Rodríguez, Mar, Mahy, Mary, Elisabeth Poulet, Harries, A, Souteyrand, Yves, Souteyrand Yves   +43 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source