Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova+3 more
wiley +1 more source
Consensus clustering based on CT radiomics has potential for risk stratification of patients with clinical T1 stage lung adenocarcinoma. [PDF]
Dong H+6 more
europepmc +1 more source
Motions of Stars in the Scattered Cluster N. G. C. 225.: (Plate 16.) [PDF]
O. J. Lee
openalex +1 more source
Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
Detection of low-altitude infrared small targets for UAVs using a density-based artificial bee colony algorithm. [PDF]
Wang H, Wang H, Han F.
europepmc +1 more source
Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman+2 more
wiley +1 more source
A robust multi-scale clustering framework for single-cell RNA-seq data analysis. [PDF]
Jiang S, Wang C, Sun Q, Zhang Z.
europepmc +1 more source
EEG Response to Sedation Interruption Complements Behavioral Assessment After Severe Brain Injury
ABSTRACT Objective Accurate assessment of the level of consciousness and potential to recover in patients with severe brain injury underpins crucial decisions in the intensive care unit but remains a major challenge for the clinical team. The neurological wake‐up test is a widely used assessment tool. However, many patients' behavioral responses during
Charlotte Maschke+12 more
wiley +1 more source
Optimization of clustering parameters for single-cell RNA analysis using intrinsic goodness metrics. [PDF]
Sciaraffa N+3 more
europepmc +1 more source