ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
DBSCAN and DBCV application to open medical records heterogeneous data for identifying clinically significant clusters of patients with neuroblastoma. [PDF]
Chicco D, Oneto L, Cangelosi D.
europepmc +1 more source
The Nuclear Star Cluster in 30 Doradus
Harlow Shapley, J. S. Paraskévopoulos
openalex +1 more source
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion+15 more
wiley +1 more source
A clustering algorithm based on grids for core data and adjacency relationships for edge data. [PDF]
He H.
europepmc +1 more source
Influence of Dystrophin Isoform Deficiency on Motor Development in Duchenne Muscular Dystrophy
ABSTRACT Objective In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increased central nervous system (CNS) involvement. We aimed to investigate how CNS involvement affects motor development in young DMD boys.
Mary Chesshyre+152 more
wiley +1 more source
Groupwise registration of infant brain diffusion tensor images using intermediate subgroup templates. [PDF]
Duan K, Li L, Calhoun VD, Shultz S.
europepmc +1 more source
Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour+6 more
wiley +1 more source
<i>De novo</i> clustering of long-read amplicons improves phylogenetic insight into microbiome data. [PDF]
Hui Y, Sandris Nielsen D, Krych L.
europepmc +1 more source