Results 211 to 220 of about 216,439 (378)

A critical review of management of allogeneic transplant‐eligible adults with Ph+ acute lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
wiley   +1 more source

Real‐world clinical experience with NGS‐based chimerism analyses in haematopoietic stem cell transplant patients

open access: yesBritish Journal of Haematology, EarlyView.
This study demonstrates the clinical utility of a next‐generation sequencing (NGS)‐based chimerism assay (CASAL) in haematopoietic stem cell transplantation (HSCT). Compared to conventional short tandem repeat (STR) methods, CASAL showed significantly higher marker informativeness, detecting mixed chimerism (MC) below 5% recipient DNA with a median of ...
Jin Ju Kim   +7 more
wiley   +1 more source

cml-biomarker-discovery

open access: yes
This repository hosts a comprehensive Python-based GUI tool designed for differential expression analysis of the RXFP1 gene and classification of chronic myeloid leukemia (CML) samples. It integrates all key components of the analysis pipeline, including preprocessing, statistical testing (t-test, Mann–Whitney U), Random Forest-based machine learning ...
openaire   +2 more sources

Different clearance of KITD816V mutation and tryptase levels after haematopoietic cell transplantation in patients with systemic mastocytosis with associated haematological neoplasm

open access: yesBritish Journal of Haematology, EarlyView.
Summary The patterns of tryptase normalization, KITD816V clearance and establishment of donor cell chimerism were analysed in 13 patients with systemic mastocytosis and associated haematological neoplasm (AHN) after haematopoietic cell transplantation (HCT).
Christian Niederwieser   +14 more
wiley   +1 more source

Myelofibrosis predicts deep molecular response 4.5 in chronic myeloid leukaemia patients initially treated with imatinib: An extensive, multicenter and retrospective study to develop a prognostic model

open access: yesClinical and Translational Medicine
Tian Zeng   +51 more
doaj   +1 more source

Priapism in CML

open access: yesIndian Journal of Medical and Paediatric Oncology, 2008
Alok Gupta   +4 more
openaire   +2 more sources

Clinical management of CMML—State of the art

open access: yesBritish Journal of Haematology, EarlyView.
Patients with chronic myelomonocytic leukaemia (CMML) typically present with clinical feature including splenomegaly, constitutional symptoms and autoimmune phenomena, as well as with pathological blood counts and biological features in the marrow. These characteristics may influence the assignment to prognostic categories such as the CPSSmol and also ...
K. Nachtkamp   +3 more
wiley   +1 more source

Artificial intelligence-driven label-free detection of chronic myeloid leukemia cells using ghost cytometry. [PDF]

open access: yesSci Rep
Suzuki K   +13 more
europepmc   +1 more source

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