Results 251 to 260 of about 195,243 (312)

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Targeting Musashi-2 to counteract senescence and resistance in chronic myeloid leukemia: enhancing the efficacy of imatinib therapy. [PDF]

BMC Cancer
Arif K, Yousaf M, Khan D.
europepmc   +1 more source

Proteomic Profiling of Imatinib-Sensitive and -Resistant K562 Cell Line to Delineate the Mechanism of Resistance in CML Blast Crisis

Neha Agrawal, Rukmini Govekar
openalex   +1 more source

Molecular Monitoring of patients with Chronic Myeloid Leukemia (CML) in the state of Qatar: Optimization of Techniques and Response to Imatinib

, 2014
Nader Al‐Dewik, Andrew P. Jewell, Mohamed A. Yassin, Hanadi Rafii El-Ayoubi, Hisham Morsi   +4 more
openalex   +1 more source

Omics and artificial intelligence integration for stratifying blast crisis CML using COSMIC signatures and pan-cancer precision drug repurposing. [PDF]

World J Clin Oncol
AlGarni A, Alanazi N, AlMukhaylid S, Alqahtani S, Almasoudi H, Samir Taleb Y, Alkhamis N, Shaheen S, Haji Siyal A, Aleem A, Naeem R, Shammas MA, Saglio G, Alroweilly D, Hussain A, Iqbal Z.   +15 more
europepmc   +1 more source

Therapeutic positioning of asciminib in chronic myeloid leukemia patients previously treated with multiple tyrosine kinase inhibitors in Qatar. [PDF]

Discov Oncol
Ghasoub R, Hamad A, El Akiki S, Fareed S, Ellahie A, Ismael O, Yassin MA.   +6 more
europepmc   +1 more source

Incidental apical left ventricular mural thrombus late after myocardial infarction with chronic myeloid leukaemia detected by cardiac magnetic resonance: a case report. [PDF]

Eur Heart J Case Rep
Nguyen QM, Almoosa F, Choong MCM, Elsmaan M, Alpendurada FD.   +4 more
europepmc   +1 more source

STAMP inhibitors and their future in CML therapy: a critical analysis. [PDF]

Blood Cancer J
Yildiz D, Eskazan AE.
europepmc   +1 more source

Evaluation of anti-proliferative and pro-apoptotic effects of tyrosine kinase inhibitors on CML-CD34+ cells.

, 2010
Devendra Hiwase
openalex   +1 more source