KF1601, a dual inhibitor of BCR::ABL1 and FLT3, overcomes drug resistance in FLT3<sup>+</sup> blast phase chronic myeloid leukemia. [PDF]
Kwon HJ+19 more
europepmc +1 more source
Nilotinib Versus Imatinib in Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph+ CML): A Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs). [PDF]
Zafar F+10 more
europepmc +1 more source
A smart pill bottle and text messaging intervention for promoting medication adherence in patients with chronic myeloid leukemia: a pilot study of txt4 TKI. [PDF]
Wen KY+7 more
europepmc +1 more source
Machine learning driven dashboard for chronic myeloid leukemia prediction using protein sequences. [PDF]
Ahmad W+5 more
europepmc +1 more source
<i>MiR-92a-1-5p</i> contributes to cellular proliferation and survival in chronic myeloid leukemia and its inhibition enhances imatinib efficacy. [PDF]
Peters J+10 more
europepmc +1 more source
Histopathological Changes as a Predictor of Fatal Outcome in Patients With Drug‐Induced Liver Injury
Liver International, Volume 45, Issue 7, July 2025.
Sabine Weber+9 more
wiley +1 more source
Natural course and biology of CML [PDF]
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder arising in the haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t(9;22) chromosomal translocation, resulting in the formation of the Philadelphia (Ph) chromosome containing the BCR-ABL1 gene.
Bradley Chereda, J. Melo
semanticscholar +4 more sources
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The interferon-alpha revival in CML
Annals of Hematology, 2015Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid leukemia (CML). Its pleiotropic mechanism of action in CML includes immune activation and specific targeting of CML stem cells. Early studies of IFNα in CML demonstrated that patients in chronic phase could attain extremely stable remissions, which correlated with ...
M. Talpaz, Jessica Mercer, R. Hehlmann
semanticscholar +4 more sources