Results 61 to 70 of about 17,015 (238)

Dormancy of growth-stunted malignant melanoma: sustainable and smoldering patterns

open access: yesOncology Reviews, 2014
The presentations of primary and metastatic cutaneous malignant melanoma (CMM) are very diverse. Evidence increasingly indicates that single CMM cells spread to distant sites quite early during cancer progression and are soon eliminated before they ...
Claudine Piérard-Franchimont   +3 more
doaj   +1 more source

Circulating tumor plasma cells quantification in newly diagnosed transplant ineligible real world multiple myeloma patients: Comparison of single‐platform flow cytometry versus next generation flow

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Circulating tumor plasma cells (CTCs) at diagnosis are independent prognostic markers in newly diagnosed multiple myeloma (NDMM). Flow cytometry (FC) enables sensitive and cost‐effective CTC quantification, but prognostic cut‐offs vary across studies.
Elona Saraci   +30 more
wiley   +1 more source

Phenotypic and transcriptomic characterization of biallelic RNU2‐2 developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective A significant proportion of individuals with suspected genetic developmental and epileptic encephalopathies (DEEs) remain unsolved following whole genome sequencing (WGS). Here we describe biallelic RNU2‐2 variants causing a recently reported, severe, recessive DEE.
Olivia J. Henry   +23 more
wiley   +1 more source

Effectiveness and safety of cannabidiol in adult patients with epilepsy: A multicenter, retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cannabidiol (CBD) has demonstrated promising effectiveness and tolerability as adjunctive treatment in patients with severe childhood epilepsies. This study investigated the effectiveness and tolerability of CBD in adults with a history of Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), or tuberous sclerosis complex (TSC ...
Sara Sánchez‐Gamino   +7 more
wiley   +1 more source

Correlation between Body Roundness Index and Cardiometabolic Comorbidities in Normal Body Weight Population: the Mediating Role of the Triacylglycerol Glucose Product Index [PDF]

open access: yesZhongguo quanke yixue
Background Due to the rise in obesity rates worldwide, the prevalence of cardiometabolic comorbidities (CMM) is increasing year by year. Body roundness index (BRI) is a new obesity measure of visceral adipose tissueand the risk of BRI and CMM in people ...
YANG Fei, HAN Zheng, FU Xiaoya, GU Handong, GU Keyi, WANG Weiqiang
doaj   +1 more source

A Cross-sectional Study of the Association of cMetS and Other Obesity Indicators with Cardiometabolic Co-morbidities in People over 35 Years of Age in Anhui Province [PDF]

open access: yesZhongguo quanke yixue
Background With the gradual aging of China's population and the gradual rise of chronic disease co-morbidities, cardiometabolic co-morbidities (CMM) have become one of the most damaging co-morbidities.
HAN Zheng, WANG Weiqiang, PAN Yaojia, FU Fanglin, SUN Meng
doaj   +1 more source

Two‐Block Paths in Oriented Graphs of Large Semidegree

open access: yesJournal of Graph Theory, EarlyView.
ABSTRACT We study the existence of oriented paths with two blocks in oriented graphs under semidegree conditions. A block of an oriented path is a maximal directed subpath. Given positive integers k $k$ and ℓ $\ell $ with k / 2 ≤ ℓ < k $k/2\le \ell \lt k$, we establish a semidegree function that guarantees the containment of every oriented path with ...
Irena Penev   +4 more
wiley   +1 more source

Assessing the State of Comprehensive Medication Management in a Sample of Primary Care Clinics

open access: yesINNOVATIONS in Pharmacy, 2019
Overview Comprehensive medication management (CMM) is an important tool to address medication-related morbidity and mortality and reduce health care costs.
Debbie Pestka   +7 more
doaj   +1 more source

Microbial and Non‐Microbial Biostimulants for Soil Health in Managed Agricultural Systems: A Scientometric Analysis of Bioinputs From 2021 to 2025

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background Biostimulants and related bioinputs encompass microbial and non‐microbial strategies used to improve plant performance, nutrient‐use efficiency, stress resilience, and soil functioning. Aim For this study, plant biostimulants were operationally defined as substances or microorganisms applied to enhance nutrient‐use efficiency ...
Enoch de Souza Ferreira   +13 more
wiley   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni   +3 more
wiley   +1 more source

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