Results 41 to 50 of about 63,222 (303)

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

open access: yesAdvanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang   +14 more
wiley   +1 more source

Gut microbiome and breastfeeding of children

open access: yesЯкутский медицинский журнал
A review of the literature on studies of the intestinal microflora in children is presented. The research for recent years has demonstrated the importance of the impact of the gut microbiome on children's health.
M. S. Savvina   +2 more
doaj   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

open access: yesAdvanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu   +12 more
wiley   +1 more source

Fuzzy predictive R2R control to CMP process

open access: yes, 2011
For chemical mechanical polishing (CMP) process characteristics of nonlinear, time-varying and not easily being in-situ measured, this paper proposes a CMP process fuzzy predictive run-to-run (R2R) controller named FPR2R.
Wang L(王亮)   +3 more
core   +1 more source

sj-pdf-1-cmp-10.1177_07388942221080105 - Supplemental material for The duration of political imprisonment: Evidence from China

open access: yes, 2022
Supplemental material, sj-pdf-1-cmp-10.1177_07388942221080105 for The duration of political imprisonment: Evidence from China by Christoph Valentin Steinert in Conflict Management and Peace ...
Christoph Valentin Steinert (12192572)
core   +1 more source

Resúmenes 1972 - 2017

open access: yesActa Médica Peruana, 2017
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Acta Medica Peruana - CMP
doaj   +1 more source

Shared reconfigurable architectures for CMPS [PDF]

open access: yes2008 International Conference on Field Programmable Logic and Applications, 2008
This paper investigates reconfigurable architectures suitable for chip multiprocessors (CMPs). Prior research has established that augmenting a conventional processor with reconfigurable logic can dramatically improve the performance of certain application classes, but this comes at non-trivial power and area costs.
Matthew A. Watkins   +2 more
openaire   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim   +12 more
wiley   +1 more source

sj-docx-1-cmp-10.1177_07388942221081103 - Supplemental material for Does transnational terrorism stimulate foreign assistance?

open access: yes, 2022
Supplemental material, sj-docx-1-cmp-10.1177_07388942221081103 for Does transnational terrorism stimulate foreign assistance?
Todd Sandler (4820361)   +1 more
core   +1 more source

Rapid identification of antibody impurities in size-based electrophoresis via CZE-MS generated spectral library

open access: yesScientific Reports
Methods for the reliable and effective detection and identification of impurities are crucial to ensure the quality and safety of biopharmaceutical products. Technical limitations constrain the accurate identification of individual impurity peaks by size-
Quan Liu   +10 more
doaj   +1 more source

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