Site‐level differences in population growth (λ) and phenotype frequencies. Mountain silhouettes represent the three study sites. Morph relative abundances are shown in the colored vertical bar. Point estimates and confidence intervals of λ for each site are displayed below, with the dashed line marking the threshold for demographic stability (λ = 1 ...
Brasil Canales‐Gordillo +4 more
wiley +1 more source
Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes +14 more
wiley +1 more source
Trends and disparities in infant mortality from intrauterine hypoxia and birth asphyxia in the United States, 1999-2023. [PDF]
Horio N +4 more
europepmc +1 more source
Laryngeal cancer mortality in the United States declined from 1999 to 2016, followed by a plateau through 2024. Disparities persist, with males and NH‐Black populations experiencing disproportionately higher mortality. Continued regional and demographic differences highlight the need to strengthen prevention, early detection, and targeted public health
Aryan Tareen +10 more
wiley +1 more source
FDG-PET/CT-based treatment response predicts recurrence and overall survival in locally advanced cervical cancer. [PDF]
Markus M +4 more
europepmc +1 more source
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth +71 more
wiley +1 more source
Correlation of Echocardiographic Right Ventricular Functional Parameters with CMR-Derived Right Ventricular Ejection Fraction in Pulmonary Hypertension: A Systematic Review and Meta-Analysis. [PDF]
Ahmed F +19 more
europepmc +1 more source
Summary Avatrombopag treatment resulted in significantly higher platelet response rates in patients when compared with placebo in a phase 3b study of patients with paediatric immune thrombocytopenia (ITP) (NCT04516967). These post hoc analyses of the 12‐week core phase further assessed the efficacy of avatrombopag, considering the influence of baseline
Rachael F. Grace +12 more
wiley +1 more source
Early quantitative stress-perfusion cardiac magnetic resonance reveals perfusion abnormalities consistent with coronary microvascular dysfunction in MINOCA patients with otherwise normal cardiac magnetic resonance findings. [PDF]
Sahar R +7 more
europepmc +1 more source
Summary Glofitamab was investigated with obinutuzumab/rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (G/R‐CHOP) in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (B‐NHL) who had ≥1 prior obinutuzumab/rituximab‐containing therapy (NCT03467373). The primary end‐point was to determine the optimal biological dose of
William Townsend +16 more
wiley +1 more source

