Results 101 to 110 of about 197,099 (282)

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

A new CNC programming method using STEP-NC protocol [PDF]

open access: yesFME Transactions, 2017
A new programming method of CNC Machine tools, which is developing as an alternative to G code, is AP238 protocol or STEP-NC, according to ISO 10303 standard.
Živanović Saša T., Vasilić Goran V.
doaj  

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

open access: yesAdvanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren   +8 more
wiley   +1 more source

Effects of nanofillers on the physical, mechanical, and tribological behavior of carbon/kenaf fiber–reinforced phenolic composites

open access: yesNanotechnology Reviews
This research investigates the effect of kenaf/carbon fiber reinforcement with the addition of nanofillers such as multi-walled carbon nanotubes (MWCNT) and cellulose nanocrystal (CNC) in the phenolic matrix composite.
Bilvatej Bramanandan   +7 more
doaj   +1 more source

A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo   +4 more
wiley   +1 more source

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

open access: yesAdvanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır   +4 more
wiley   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Pembangunan Modul Pengajaran Kendiri (MPK) keusahawanan dalam topik isu keusahawanan bagi pelajar diploma di politeknik [PDF]

open access: yes, 2004
Terdapat pelbagai kaedah pembelajaran yang telah diperkenalkan termasuklah kaedah pembelajaran yang menggunakan pendekatan pembelajaran bermodul secara kendiri.
Shaik Ismail, Siti Mahani
core  

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

open access: yesAdvanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie   +8 more
wiley   +1 more source

System for Automated Production of Custom Made Shoe Insoles

open access: yesJournal of Mechanical Engineering
This article presents the development and implementation of the IPASIOU automated system for producing orthopaedic insoles. The IPASIOU system utilizes CAD/CAM technologies, digital scanning, and automated manufacturing processes to enhance the quality ...
Obrovac Karlo   +3 more
doaj   +1 more source

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