Results 31 to 40 of about 5,076 (221)

Design and Performance Study of a Compliant Mechanism Capable of Achieving Dual-Range Constant Force Output

open access: yesMicromachines
A compliant constant-force mechanism (CCFM), known for its frictionless, contact-free operation and inherently constant output, is typically limited to a single force range, restricting its adaptability to multi-task applications. To address this problem,
Chongchong Xu   +8 more
doaj   +1 more source

Fog Computing-Based Cyber-Physical Machine Tool System

open access: yesIEEE Access, 2018
As one kind of significant manufacturing equipment, computer numerical control (CNC) machine tools have to be endowed with new functions to meet the requirements of processing devices in the era of “Industry 4.0.”Inter-connection and ...
Zude Zhou   +5 more
doaj   +1 more source

Joint Optimization Strategy of Predictive Maintenance and Tool Replacement for Energy Consumption Control

open access: yesShanghai Jiaotong Daxue xuebao, 2020
With the rise of sustainable development and energy-saving mode in the manufacturing industry, a joint optimization strategy of machine predictive maintenance and tool replacement is proposed aiming to meet the needs of energy control and maintenance ...
SHI Guo   +4 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

Strain-rate-dependent dislocation-martensite interactions in Fe-Mn-Al-Nb medium manganese steel via discrete dislocation dynamics modeling

open access: yesMaterials & Design
Medium manganese steels (MMnS) exhibit exceptional strength-ductility synergy due to the well-known transformation induced plasticity (TRIP) effects, making it a prime candidate for automotive lightweighting and safety–critical structures.
Ning Guo   +3 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Research on On-Line Precision Measurement System of Rolling Bearing Roundness

open access: yesJournal of Manufacturing and Materials Processing
High-precision rolling bearing applications are widely used in aerospace, new energy vehicles and high-end equipment. However, high-precision bearing manufacturing has always been one of the hot topics of research.
Lei Zhao   +4 more
doaj   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng   +7 more
wiley   +1 more source

A Comprehensive Review of Robotic Grinding Technology

open access: yesMachines
Integrated die-cast components reduce machining/assembly steps and improve mechanical dynamic characteristics, eliminating joint loosening/fracture risks after long-term use.
Jinwei Qiao   +6 more
doaj   +1 more source

A Biomimetic Solvatochromic Chip With Optimized Chemical Diversity for On‐Site Liquid Identification

open access: yesAdvanced Science, EarlyView.
A compact biomimetic photonic‐gustatory chip uses Hansen‐solubility‐parameter‐guided solvatochromic disks to create distinct color patterns in organic liquids. An optimized four‐disk array distinguishes solvent types, ratios, homologues, isomers, and alcoholic beverages. Coupled with smartphone imaging and deep learning, it identifies 80 liquid classes
Jintao Zhang   +9 more
wiley   +1 more source

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