Results 31 to 40 of about 3,982 (194)

Variational Analysis for CNC Milling Process

Procedia CIRP, 2016
AbstractDimensional and geometrical defects severely affect the quality of chip removal processes in CNC machines. In order to improve the accuracy, a long and expensive calibration process is usually performed on the CNC machine. The tuning process could be easier and faster if the designer is able to evaluate the effect of error sources providing a ...
AFKHAMIFAR, ARMIN, ANTONELLI, DARIO, CHIABERT, Paolo   +2 more
openaire   +3 more sources

The milling parameters of mechanical parts are optimized by NC machining technology

Frontiers in Mechanical Engineering
In the field of mechanical manufacturing, CNC machining technology plays an important role in improving the precision and efficiency of part processing. However, how to further improve the effect of NC machining by optimizing milling parameters is still ...
Zairu Wang
doaj   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

The Optimization of Machining Parameters for Milling Operations by Using the Nelder–Mead Simplex Method

Journal of Manufacturing and Materials Processing, 2020
The purpose of machining operations is to make specific shapes or surface characteristics for a product. Conditions for machining operations were traditionally selected based on geometry and surface finish requirements.
Yubin Lee, Alin Resiga, Sung Yi, Chien Wern   +3 more
doaj   +1 more source

Automatic Generating CNC-Code for Milling Machine

, 2013
G-code is the main factor in computer numerical control (CNC) machine for controlling the tool-paths and generating the profile of the object's features. For obtaining high surface accuracy of the surface finish, non-stop operation is required for CNC machine.
Chalakorn Chitsaart, Suchada Rianmora, Mann Rattana-Areeyagon, Wutichai Namjaiprasert   +3 more
openaire   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Photochemical Fuel Carrier Molecules for Robotic Embodied Energy

Advanced Materials, EarlyView.
We designed a novel fuel carrier photoresponsive molecule for on‐demand energy storage and release. Carrier molecules undergo bond scission under UV light to release chemical fuel and locally generate propulsive Marangoni flows. We demonstrate this photochemical embodied energy strategy in small‐scale robots and active matter systems, enabling ...
Chuqi Huang, Songah Jeong, Ji Woo Kim, Kanyarat Mantala, Zenghao Zhang, Hyungwoo Kim, Abdon Pena‐Francesch   +6 more
wiley   +1 more source

Roadmap to Precision 3D Printing of Cellulose: Rheology‐Guided Formulation, Fidelity Assessment, and Application Horizons

Advanced Materials Technologies, EarlyView.
This critical review presents a comprehensive roadmap for the precision 3D printing of cellulose. Quantitative correlations link ink formulation and rheological properties to print fidelity and final material performance. This framework guides the development of advanced functional materials, from biomedical scaffolds to electromagnetic shielding ...
Majed Amini, Hadi Hosseini, Seyyed Alireza Hashemi, Mohammad Arjmand   +3 more
wiley   +1 more source