Results 41 to 50 of about 31,980 (230)

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Peningkatan Kemampuan Sistem Operasi Mesin Milling Cnc Trainer Dengan Mengadaptasi Luaran Perangkat Lunak Mastercam [PDF]

, 2017
Kebutuhan operator semakin meningkat dengan semakin meningkatnya persaingan antar Perusahaan. Namun, hal ini masih menjadi persoalan. SMK tidak dapat menghasilkan operator yang berkompeten dikarenakan SMK belum bisa menyediakan mesin CNC (Computer ...
Ulinuha, C. (Cipto), Widyanto, S. A. (Susilo)   +1 more
core  

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

The Optimization of Machining Parameters for Milling Operations by Using the Nelder–Mead Simplex Method

Journal of Manufacturing and Materials Processing, 2020
The purpose of machining operations is to make specific shapes or surface characteristics for a product. Conditions for machining operations were traditionally selected based on geometry and surface finish requirements.
Yubin Lee, Alin Resiga, Sung Yi, Chien Wern   +3 more
doaj   +1 more source

Automatic Generating CNC-Code for Milling Machine

, 2013
G-code is the main factor in computer numerical control (CNC) machine for controlling the tool-paths and generating the profile of the object's features. For obtaining high surface accuracy of the surface finish, non-stop operation is required for CNC machine.
Chalakorn Chitsaart, Suchada Rianmora, Mann Rattana-Areeyagon, Wutichai Namjaiprasert   +3 more
openaire   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla Iglesias García, Jagoda Litowczenko‐Cybulska, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Analysis of cutting parameters in point machining of parts with complex shape [PDF]

, 2018
This paper presents developed SW module in the postprocessor, which is designed to backward analysis of CAM milling toolpath. The module is designed to analyze multi-axis finishing machining of complex shape parts with milling cutters with a circular ...
Rybín J., Stejskal M., Vavruška P., Zeman P.   +3 more
core  

A simulated investigation on the machining instability and dynamic surface generation [PDF]

, 2005
In this paper, the authors propose the generic concept of machining instability based on the analysis of all kinds of machining instable behaviors and their features.
Altintas, Altintas, Budak, Burns, Davies, Davies, K. Cheng, Marsh, Stepan, Tlusty, Wiercigroch, X.C. Luo, X.K. Luo, X.W. Liu   +13 more
core   +1 more source

Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites

Advanced Materials, EarlyView.
Co‐cultivation of the cellulose‐producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen‐generating sites throughout the medium. This symbiotic platform supports 3D cellulosic constructs with geometries dictated by the vessel shape.
Kui Yu, Sing Teng Chua, Ran Zhao, Alyssa Smith, Michael Kühl, Alison G. Smith, Tom Ellis, Silvia Vignolini   +7 more
wiley   +1 more source

Multiplexed Luminal Tissue Constructs with Reconfigurable Barriers for Dynamic Modeling of Multi‐Tissue Interactions

Advanced Materials Technologies, EarlyView.
This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun, José A. Jiménez‐Torres, Chao Li, Jose M. Ayuso, Karina Lugo‐Cintron, Joseph Ulbrich, Benjamin Myers, Sheena C. Kerr, Adeel Ahmed, David J. Beebe   +9 more
wiley   +1 more source