Results 11 to 20 of about 41,248 (200)

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Sterile neutrinos at the CNGS [PDF]

open access: yesJournal of High Energy Physics, 2007
We study the potential of the CNGS beam in constraining the parameter space of a model with one sterile neutrino separated from three active ones by an O(eV^2) mass-squared difference, Δm^2_SBL. We perform our analysis using the OPERA detector as a reference (our analysis can be upgraded including a detailed simulation of the ICARUS detector). We point
Donini, A   +4 more
openaire   +3 more sources

Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation [PDF]

open access: yes, 1997
Most working proteins, including metabolic enzymes, transcription regulators, and membrane receptors, transporters, and ion channels, share the property of allosteric coupling. The term 'allosteric' means that these proteins mediate indirect interactions
Lester, Henry A.   +2 more
core   +1 more source

The hot pick-up technique for batch assembly of van der Waals heterostructures

open access: yesNature Communications, 2016
The reliable assembly of two-dimensional materials into van der Waals heterostructures is a critical step towards nanoscale electronic integration. Here the authors present a technique for batch fabrication of graphene/boron nitride stacks with clean ...
Filippo Pizzocchero   +7 more
doaj   +1 more source

Conductance quantization suppression in the quantum Hall regime

open access: yesNature Communications, 2018
Conductance quantization is the hallmark of non-interacting confined systems. The authors show that the quantization in graphene nanoconstrictions with low edge disorder is suppressed in the quantum Hall regime.
José M. Caridad   +8 more
doaj   +1 more source

Conversion of Gasoline Vehicles to CNG Hybrid Vehicles (CNG-Electric Vehicles) [PDF]

open access: yesResearch Journal of Applied Sciences, Engineering and Technology, 2013
The aim of this study is investigation of the feasibility and advantages of using the natural gas as an alternative to gasoline as a fuel for hybrid electric vehicles. Operating CNG vehicles are really beneficial in the Middle East region considering the fact that gasoline is offered at a heavily subsidized price and therefore, by converting a ...
Hassan Moghbelli   +1 more
openaire   +1 more source

An Experimental Study on the Performance and Emission of the diesel/CNG Dual-Fuel Combustion Mode in a Stationary CI Engine

open access: yesEnergies, 2019
One of the possibilities to reduce diesel fuel consumption and at the same time reduce the emission of diesel engines, is the use of alternative gaseous fuels, so far most commonly used to power spark ignition engines.
Arkadiusz Jamrozik   +2 more
doaj   +1 more source

cGMP Analogues with Opposing Actions on CNG Channels Selectively Modulate Rod or Cone Photoreceptor Function

open access: yesPharmaceutics, 2022
The vertebrate retina harbors rod and cone photoreceptors. Human vision critically depends on cone photoreceptor function. In the phototransduction cascade, cGMP activates distinct rod and cone isoforms of the cyclic nucleotide-gated (CNG) channel ...
Sophie Wucherpfennig   +9 more
doaj   +1 more source

A regenerative supercritical-subcritical dual-loop organic Rankine cycle system for energy recovery from the waste heat of internal combustion engines [PDF]

open access: yes, 2017
Organic Rankine cycle (ORC) system is considered as a promising technology for energy recovery from the waste heat rejected by internal combustion (IC) engines.
Wang, Enhua   +3 more
core   +1 more source

Voltage Sensing in CNG Channels [PDF]

open access: yesBiophysical Journal, 2011
Gating of cyclic nucleotide gated (CNG) channels is thought not to be voltage dependent. However, in the presence of symmetrical Rb+ and Cs+ CNGA1 channels exhibit a clear voltage and time dependent gating of macroscopic current. In symmetrical Rb+ and Cs+ the single channel conductance (γsc) and the open probability (Pop) of w.t.
Marchesi A   +2 more
openaire   +1 more source

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