Results 111 to 120 of about 67,701 (309)
Serological evidence for multiple strains of canine norovirus in the UK dog population.
PLoS ONE, 2013 Noroviruses are associated with intestinal disease in humans, cows, pigs, mice, and, more recently, dogs. In 2007, the first canine norovirus (CNV) was identified and characterized in Italy.
Sarah Caddy +6 more
doaj +1 more source
Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen +13 more
wiley +1 more source
CNV calling, analysis, filtering methodology and results. [PDF]
, 2019 In addition to GC waviness correction and log2 ratio filtering, we applied a rigid quality control pipeline at sample, CNV and annotation levels to identify disease-associated CNV candidates.
Peter Andrews (45652) +9 more
core +1 more source
Frontiers in MedicinePurposeCopy number variation sequencing (CNV-Seq) has become a first-line prenatal diagnostic technology. The purpose of this study was to investigate the changes in the target population for prenatal diagnosis in the CNV-Seq era and to assess the ...
Shaozhe Yang +13 more
doaj +1 more source
Genetics Selection Evolution, 2018 Background Copy number variations (CNV) are an important source of genetic variation that has gained increasing attention over the last couple of years.
Wioleta Drobik-Czwarno +3 more
doaj +1 more source
Prevalence of Phelan McDermid Syndrome Estimated To Be ~1:7300 Using a Multisource Model
Autism Research, EarlyView.ABSTRACT Estimating the prevalence of genetic disorders is complicated by many factors including sampling bias and differing methods of estimation. However, establishing the true prevalence of these disorders is critical for understanding disease burden, pharmacoeconomic modeling, and resource allocation for testing and care.
Tess Levy +22 more
wiley +1 more source
Mouse Laser-Induced CNV Assay. [PDF]
, 2014 (A) Subretinal injection of MSA-CEP does not increase CNV area compared to mice injected with saline or MSA-CTL2. Bar graph shows mean area of CNV +/− SEM from first experiment evaluating the effect of subretinal injection of saline, 0.5 µg of rhVEGF165,
Bruce Jaffee (649237) +26 more
core +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao +10 more
wiley +1 more source
Transpupillary thermotherapy of occult CNV with no or minimally classic CNV in age-related macular degeneration [PDF]
, 2001 Transpupillary thermotherapy (TTT) has been suggested as a putative treatment for choroidal neovascularization (CNV) in age-related macular degeneration (AMD).
Seregard, S,, Libert, C, Algvere, PV
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.CYP2D6 metabolizes about 20% of commonly used drugs, including tamoxifen, a major hormone therapy for breast cancer. Although the relationship between tamoxifen pharmacokinetics and CYP2D6 genotype has been demonstrated, residual variability in drug exposure remains unexplained.
Jeanne Petit +7 more
wiley +1 more source