Results 81 to 90 of about 258,611 (262)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Health policy and systems research collaboration pathways: lessons from a network science analysis
Health Research Policy and Systems, 2017 Background The 2004 Mexico Declaration, and subsequent World Health Assembly resolutions, proposed a concerted support for the global development of health policy and systems research (HPSR).
Krista M. English, Babak Pourbohloul
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gender gaps in Australian research publishing, citation and co-authorship. [PDF]
Scientometrics, 2023 Jamali HR, Abbasi A.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
International Journal of Information Science and Management, 2022 As one of the main bibliometric concepts, co-authorship has been thoughtfully considered in recent years. Despite many bibliometric studies on the co-authorship in different scientific fields and worldwide countries/regions, Iranian researchers ...
Mohammad Karim Saberi +4 more
doaj
Social stratification in networks: insights from co-authorship networks. [PDF]
J R Soc Interface, 2023 Jalali ZS, Introne J, Soundarajan S.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Patterns of collaboration and knowledge generated by an Australian rural research centre over 20 years: a co-authorship network analysis. [PDF]
Health Res Policy Syst, 2023 Bailie J, Matous P, Bailie R, Passey ME.
europepmc +1 more source