Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma [PDF]
Nature Communications, 2023 Interplay between chromatin-associated complexes and modifications critically contribute to the partitioning of epigenome into stable and functionally distinct domains.
Xiao Chen +16 more
doaj +2 more sources
Co-dependency for MET and FGFR1 in basal triple-negative breast cancers [PDF]
npj Breast Cancer, 2021 Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks both effective patient stratification strategies and therapeutic targets. Whilst elevated levels of the MET receptor tyrosine kinase are associated with TNBCs and predict poor ...
Vanessa Y. C. Sung +9 more
doaj +2 more sources
Depressive symptoms and co-dependency in caregiver of patients with chronic heart failure [PDF]
European Psychiatry, 2023 Introduction Chronic heart failure causes serious mental problems in the life of the patient and caregiver due to symptoms and repeated hospitalizations.
A. Yıldırım, S. Karaca
doaj +2 more sources
Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer [PDF]
Cell Reports, 2018 Summary: Cancer cells overexpress a diversity of anti-apoptotic BCL-2 family proteins, such as BCL-2, MCL-1, and BFL-1/A1, to enforce cellular immortality.
Rachel M. Guerra +7 more
doaj +2 more sources
Parental Psychological Profiles in Autism and Other Developmental Contexts: A Latent Profile Analysis Informing Coordinated Family-Centered Care [PDF]
ChildrenBackground: Autism spectrum disorder (ASD) or psychiatric conditions, special education needs and addictions exert substantial demands on families, yet parental psychological functioning remains insufficiently integrated into prevention and family-based ...
Margarita Bakracheva +4 more
doaj +2 more sources
Tumor cell villages define the co-dependency of tumor and microenvironment in liver cancer [PDF]
Nature CommunicationsSpatial cellular context is crucial in shaping intratumor heterogeneity. However, understanding how each tumor establishes its unique spatial landscape and what factors drive the landscape for tumor fitness remains significantly challenging.
Meng Liu +9 more
doaj +2 more sources
Integrative Pan-Cancer Mapping of Proteasome Dependency Prioritizes PSMB5 and PSMB6 as Context-Dependent Vulnerability Biomarkers Linked to Immune Context [PDF]
MoleculesThe prioritization of biomarkers that inform molecular-targeted cancer research remains challenging because tumor vulnerabilities are context-dependent.
Jeong Han Kim +6 more
doaj +2 more sources
The Mediating Role of Self-Differentiation in the Relationship between Emotional Abuse and Co-Dependency in married female students [PDF]
مطالعات زن و خانواده, 2021 One of the problems that families are involved with is the experience of violence, especially Emotional Abuse. The purpose of this study was to investigate the mediating role of Self-Differentiation between the components of Co-Dependency and Emotional ...
Vafa Mostafa +3 more
doaj +1 more source
Co-Depedency between Single Mother and Her Son in Mother (2020)
Japanology, 2023 Co-dependency can occur in any kind of relationships, such as husband and wife, friends, and even parents and children. This phenomenon is being represented in media, such as movie titled Mother by Tatsushi Omori.
Devina Nur Rahmawati +1 more
doaj +1 more source
Cogent Public Health, 2022 : Pethidine is a short and fast-acting synthetic opioid that has a high potential for abuse and addiction compared to other opioids. It is popularly used in the management of pain such as pancreatitis, and cholecystitis peri- and post-operations.
Raymond Odokonyero +3 more
doaj +1 more source