Results 181 to 190 of about 164,630 (260)

Dysregulated AKT signaling reprograms osteosarcoma to drive selective reliance on EP300. [PDF]

J Exp Med
Delahunty IM, Nance S, Zhang Y, Lamoureux F, Liu Q, Wright WC, Ritter KE, Shendy NAM, Brounais-Le Roye B, Kietlinska SJ, Mohammad Nezhady MA, Feng Y, De Kegel B, Rees MG, Kocak M, George AB, Lu M, Kavirayani AM, Wang B, Liu Y, Prinsen PEA, Khashana Y, Ebegboni VJ, Ronan MM, Roth JA, Sweet-Cordero EA, Guenther LM, Geeleher P, Ma X, Ory B, Qi J, Abraham BJ, Durbin AD.   +32 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The Role of Early Visual Experience in Cross-Signal Dependency Detection. [PDF]

Dev Sci
Gupta P, Vogelsang L, Vogelsang M, Khemani N, Jain M, Lall N, Verma D, Ralekar C, Ganesh S, Sinha P.   +9 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A proposed nine-domain nutrient-function architecture for modelling adult nutrient adequacy across dietary preference variants and calorie tiers. [PDF]

Front Nutr
Singh V.
europepmc   +1 more source

State-matched redox nanomedicine for cell fate control and multicompartment therapeutic windows. [PDF]

Redox Biol
Li J, Liu J, Cai J, Xu T, Gao K, Zhang J, Luo N, Wang Y, Xie Y, Peng X.   +9 more
europepmc   +1 more source

WDR12 Promotes Glucose Metabolism via PFKFB4 Upregulation in Gastric Cancer. [PDF]

Cancer Sci
Zhang R, Liu D, Feng X, Cheng A, Yang Z, Zhang K.   +5 more
europepmc   +1 more source