Results 41 to 50 of about 360,300 (238)

Synergistic Effects of Anaerobic Co-Digestion of Chicken Manure and Corn Stover in Batch and Continuous Modes

open access: yesFermentation, 2023
The present study aimed to evaluate the anaerobic co-digestion process of chicken manure and corn stover to identify the key parameters that influence methane production. Results from both batch and semi-continuous tests showed that co-digestion enhanced
Xinhui Yu   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A review on the operational parameters and degradation kinetics used in anaerobic co-digestion of tannery residues

open access: yesWaste Management Bulletin
Tannery residues possess the potential to produce biogas through anaerobic co-digestion processes. Research related to anaerobic co-digestion of food wastes and easily biodegradable wastes is ongoing and a vast advancement has been observed already to ...
Shilpy Rani Basak   +5 more
doaj   +1 more source

Biogas Production from the Co- and Tri-digestion of Pineapple Wastes with Food Wastes and Pig Manure [PDF]

open access: yesE3S Web of Conferences
Anaerobic digestion (AD) of pineapple wastes (PW) was determined to observe its effects on biogas production when co- and tri-digested with pig manure (PM) and food waste (FW). The highest cumulative biogas yield was seen in R3 (245 mL/g VS), followed by
Avena Louise Grace   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Co-Digestion of Napier Grass and Its Silage with Cow Dung for Methane Production

open access: yesEnergies, 2017
Methane production from co-digestion of grass with cow dung and silage with cow dung was conducted by a bioaugmentation technique. For self-fermentation, maximum methane yield (MY) of 176.66 and 184.94 mL CH4/g-VSadded were achieved at a ratio of grass ...
Wipa Prapinagsorn   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Anaerobic Digestion of the Halophyte Salicornia ramosissima in Co-Digestion with Swine Manure in Lab-Scale Batch and Continuous Reactor Tests

open access: yesEnergies
This laboratory study investigated the anaerobic co-digestion process of the halophyte S. ramosissima (Sram) together with swine manure (SM) in different mixing ratios in batch and continuous reactor experiments. In the batch experiments, a methane yield
Aadila Cayenne, Hinrich Uellendahl
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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