FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
A New Integrative Model For The Co-Occurrence of Non-Suicidal Self-Injury Behaviours and Eating Disorder Symptoms [PDF]
, 2021 Isabel Krug +8 more
openalex +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Classification of brain states that predicts future performance in visual tasks based on co-integration analysis of EEG data. [PDF]
R Soc Open Sci, 2022 Levakova M, Christensen JH, Ditlevsen S.
europepmc +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
The evaluation of output convergence in several Central and Eastern European countries
Ekonomika, 2015 The main objective of this study is to check the convergence in output for six countries from Central-Eastern Europe that are also members of the European Union.
Simionescu M.
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Scientific ReportsAlzheimer's disease (AD) is a neurodegenerative disease that commonly causes dementia. Identifying biomarkers for the early detection of AD is an emerging need, as brain dysfunction begins two decades before the onset of clinical symptoms.
Takaki Oka +6 more
doaj +1 more source
Are Slovak Retail Gasoline and Diesel Price Reactions on Crude Oil Changes Asymmetric? [PDF]
Statistika: Statistics and Economy Journal, 2020 The paper explains why the Slovak retail gasoline and diesel prices rise more rapidly when the price of crude oil increases and fall slowly when the price of crude oil decreases.
Karol Szomolányi +2 more
doaj
Impact of oil prices, the U.S interest rates on Turkey's real estate market. New evidence from combined co-integration and bootstrap ARDL tests. [PDF]
PLoS One, 2021 Alhodiry A, Rjoub H, Samour A, Samour A.
europepmc +1 more source