Results 101 to 110 of about 6,829,809 (314)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Co-occurrence of VIM-positive non-

Heliyon
Background: Pseudomonas aeruginosa is a bacterial pathogen responsible for severe hospital-acquired infections, and is capable of forming persistent reservoirs in hospital sink drains, creating a transmission risk.
Jannette Pirzadian, Willemien H.A. Zandijk, Astrid P. Heikema, Heidy H.H.T. Koene, Wil H.F. Goessens, Margreet C. Vos, Corné H.W. Klaassen, Juliëtte A. Severin   +7 more
doaj   +1 more source

Co-occurrence histogram for an part.

, 2017
The normalized co-occurrence histogram represents the distribution of distances (offsets) of subparts that activate simultaneously. The distances are shown relative to a chosen central part.
Matevž Pesek (3612350), Aleš Leonardis (3612347), Matija Marolt (3612353)   +2 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Novel Co‐Occurrence of Trisomy 21 and Heterozygous CFTR Mutation

Respirology Case Reports
The coexistence of trisomy 21 and cystic fibrosis (CF) is extremely rare, with fewer than 10 reported cases, all involving homozygous CFTR mutations. However, the impact of a heterozygous CFTR mutation in a patient with trisomy 21 remains unexplored.
Majd Oweidat, Tamer Qutaina, Alzahra Akram Hamdan, Fatima Zain Hanini   +3 more
doaj   +1 more source

Co-occurrence matrices for the White Sea dataset and subsets.

, 2022
Co-occurrence matrices for species showing significant associations in (a) the Russian White Sea metacommunity, (b) the White Sea middle shelf metacommunity, and (c) the White Sea deep subtidal metacommunity.
Emily G. Mitchell (8706969), Rebecca Eden (12557521), Andrea Manica (167050)   +2 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Co-occurrence matrices.

, 2012
A) Average over ten restarts of the co-occurrence matrices for clustering with a fixed number of clusters. Number of clusters K is indicated in each plot. Matrices were ordered for visualization using optimal leaf ordering.
Matthijs Verhage (67658), L. Niels Cornelisse (67656), Tom Heskes (173116), Tjeerd M. H. Dijkstra (173108), Evgeni Tsivtsivadze (173099), Marieke Meijer (173103)   +5 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

A guide for comparing microbial co‐occurrence networks

iMeta, 2023
Chi Liu, Chaonan Li, Yanqiong Jiang, Raymond J. Zeng, Minjie Yao, Xiangzhen Li   +5 more
doaj   +1 more source