Results 51 to 60 of about 766,173 (279)

Identification of discriminant features from stationary pattern of nucleotide bases and their application to essential gene classification

open access: yesFrontiers in Genetics, 2023
Introduction: Essential genes are essential for the survival of various species. These genes are a family linked to critical cellular activities for species survival.
Ranjeet Kumar Rout   +7 more
doaj   +1 more source

Evolution of worldwide stock markets, correlation structure and correlation based graphs

open access: yes, 2011
We investigate the daily correlation present among market indices of stock exchanges located all over the world in the time period Jan 1996 - Jul 2009. We discover that the correlation among market indices presents both a fast and a slow dynamics.
A. Z. Gorski   +6 more
core   +1 more source

Automated screening of MRI brain scanning using grey level statistics [PDF]

open access: yes, 2016
This paper describes the development of an algorithm for detecting and classifying MRI brain slices into normal and abnormal by relying on prior-knowledge, that the two hemispheres of a healthy brain have approximately a bilateral symmetry.
Hasan, A, Meziane, F
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Color and cross diagonal symmetric pair co-occurrence matrix [PDF]

open access: yesIndian Journal of Science and Technology, 2020
Objectives: The main goal of this study is to derive an efficient feature vector to capture both the color and texture information. This makes the proposed descriptor as a multipurpose descriptor. Methodology: This study derived color information by combining the individual histograms of H, S and V plane.
openaire   +1 more source

ESG: Extended Similarity Group method for automated protein function prediction [PDF]

open access: yes, 2008
We present here the Extended Similarity Group (ESG) method, which annotates query sequences with Gene Ontology (GO) terms by assigning probability to each annotation computed based on iterative PSI-BLAST searches.
Changsoon Park   +3 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Pengenalan Ras Berdasarkan Hidung Dan Mulut Menggunakan Gray Level Co-Occurrence Matrix

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer, 2021
Ras dapat digunakan untuk mengkategorikan manusia dalam populasi atau kelompok besar. Oleh karena itu, pengenalan ras dapat berguna untuk mempermudah dalam mengidentifikasi seseorang dan membantu dalam mempersempit lingkup pencarian.
Ema Rachmawati   +2 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

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