Results 41 to 50 of about 6,365,962 (295)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Construction quality supervision of oil & gas storage and transportation projects: challenges and innovative pathways

管道保护
As the lifeline of national energy security, oil and gas storage and transportation projects directly impacts energy supply stability and public safety. Their construction quality serves as the core support to deliver the goals of increasing oil and gas ...
Langbo CHEN, Dechao YANG, Xinyu LU
doaj   +1 more source

Green Transformational Leadership: Bridging the gap between Green HRM Practices and Environmental Performance through Green Psychological Climate

Sustainable Futures, 2023
Based on the Resource-Based View theory, this study explores the impact of Green Human Resource Management on Environmental Performance. Additionally, this study assesses the mediating effect of Psychological Green Climate between Green Human Resource ...
Zainab Younis, Sajjad Hussain
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Effect of Driving Sound of Electric Vehicle on Product Attractiveness

Human-Centric Intelligent Systems, 2023
Product sounds are an effective means of communicating product features. However, the existing research on electric vehicle (EV) driving sounds has focused on noise reduction and pedestrian safety.
Takumi Kato, Ryuji Yokote
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Co-operation, learning and co-operative values

Journal of Education Policy, 2016
Review of Woodin, Tom (editor) (2015) Co-operation, Learning and Co-operative Value, Abingdon: Routledge.
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Dynamic Response Characteristics of Ballooning Effect in Deep Fractured High Temperature High Pressure Formations in Deep Water Drilling

Zuanjingye yu wanjingye
Deep formations in deep water area are developed with fractures and fissures, fluctuations in wellbore pressure during drilling can easily induce ballooning effect which is made complex by the high temperature high pressure (HTHP) downhole environment ...
Yanhui WU, Honglin HUANG, Ming LUO, Wentuo LI, Chuanhua MA, Rui DAI, Jun LI   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source