Results 251 to 260 of about 4,176,116 (313)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

NRG Oncology and Particle Therapy Co-Operative Group Patterns of Practice Survey and Consensus Recommendations on Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy and Hypofractionated Radiation Therapy for Thoracic Malignancies. [PDF]

open access: yesInt J Radiat Oncol Biol Phys
Liu W   +15 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source
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Co-operation and Co-operatives in 21st-Century Europe

2023
The book brings together examples of co-operation and co-operatives from around Europe that investigate different instances of grass roots co-operative ventures on the ground. These examples are brought into the context of the 21st century as a contribution to socio-economic reflections on how Western society, principally in Europe but with possible ...
  +5 more sources

Co-operation and Timing [PDF]

open access: possibleSSRN Electronic Journal, 2000
If players cannot perfectly synchronize their actions in a coordination game, an efficient outcome will never be achieved.
openaire   +1 more source

Co-Operatives

2019
This chapter explores the strategic response of co-operative management toward globalization and the resulting outcome. It aims to develop the tensions which large-scale co-operatives need to address in the context of global pressures. The chapter discusses how the identified tensions impacted the co-operative sector in Denmark and how it has come to ...
Mordhorst, Mads, Jensen, Kristoffer
openaire   +4 more sources

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