Results 101 to 110 of about 80,021 (301)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Property and Its Role as Interpreted by Polish Agrarianists, 1933-1946

open access: yesStudia Historiae Oeconomicae, 2011
In the conception of ownership formulated by Polish agrarianists the creation of a new socio-economic system, pluralistic with regard to the forms of ownership, based on small private ownership in agriculture, crafts and retail trade as well as co ...
Tadeusz Janicki
doaj  

Applying the Apriori algorithm for investigating the relationships between demographic characteristics of Iranian top 100 enterprises and the strcture of their commercial website

open access: yes, 2013
This study was conducted with the main aim to investigate the relationships between demographic characteristics of companies and the facilities required for their commercial websites.
Azimi, Ali, Kaffashpour, Azar
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Land consolidation from a comparative perspective: Legal inspirations for Slovakia

open access: yesPrawne Problemy Górnictwa i Ochrony Środowiska
Land consolidation is a legal instrument for the adjustment of land ownership, present in various forms across many countries in Europe. Land ownership, by its very nature, constitutes a prerequisite for the performance of numerous human activities ...
Ludovit Macaj
doaj   +1 more source

MISSIONS FOR EU INNOVATION POLICY WHY THE RIGHT SET-UP MATTERS. Bertelsmann Stiftung Policy Paper N0. 224 29 May 2018 [PDF]

open access: yes, 2019
The proposed introduction of research & innovation (R&I) missions in Horizon Europe, the next EU research programme, seems to be the most significant and ambitious change on previous programmes, especially given its implications for the governance of ...
Ständer, Philipp
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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