Results 61 to 70 of about 68,605 (254)

The Law of Worker Ownership

open access: yesOsgoode Hall Law Journal, 1989
This article discusses Canadian, U.K., U.S., French, and Swedish models of worker ownership and the legal principles which apply to them. Based on the evidence that, in contrast to other traditional forms of workplace organization, worker participation ...
Christopher S. Axworthy, David Perry
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Teachers Co-Designing and Implementing Career-Related Instruction

open access: yesEducation Sciences, 2019
Teachers encounter the challenge of how to provide students adequate awareness of science-related careers. Therefore, innovative teaching material for promoting science-related careers needs to be designed.
Anssi Salonen   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Arts-Based Methods as Tools for Co-design in a South African Community-based Design Co-operative

open access: yesCubic Journal, 2018
Arts and visual participatory methods can be effective tools to facilitate the experience of rural design actors involved in a co-design process that could be seen as contributions to the emerging praxis called “Design Social.” We identify the inclusion ...
Khaya Mchunu, Kim Berman
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Co-ownership

open access: yes, 2016
La propriété privée est souvent assimilée à la seule propriété individuelle. Pourtant, le droit positif connaît de nombreuses institutions permettant d'assurer une appropriation en commun, qu'il y ait ou non personne morale (indivision, communauté entre époux, sociétés, copropriétés spéciales, cotitularité, etc.).
openaire   +3 more sources

EL DERECHO ROMANO Y EL CÓDIGO CIVIL EN EL JAPÓN MODERNO: SISTEMÁTICA, PROPIEDAD Y COPROPIEDAD ROMAN LAW STUDIES AND THE CIVIL CODE IN MODERN JAPAN: SYSTEM, OWNERSHIP AND CO-OWNERSHIP

open access: yesRevista Chilena de Derecho, 2009
RESUMEN: El presente artículo trata de la recepción del Derecho romano en Japón como parte de la modernización de la Era Meiji. Asimismo, desarrolla la sistemática del Código Civil japonés, especialmente en materia de propiedad, para centrarse finalmente
Tomoyoshi Hayashi
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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