Results 91 to 100 of about 17,950 (258)

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

British Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

Predict less, prevent more: A familiar mantra for sickle cell anaemia?

British Journal of Haematology, EarlyView.
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley   +1 more source

Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

British Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet, Priscilla Boizeau, Zinedine Haouari, Berengère Koehl, Monique Elmaleh, Emmanuelle Lesprit, Florence Missud, Ghislaine Ithier, Laurent Holvoet, Valentine Brousse, Christophe Delclaux, André Denjean, Suzanne Verlhac, Corinne Alberti, André Baruchel, Nathalie Couque, Malika Benkerrou   +16 more
wiley   +1 more source

Validation of Noninvasive Methemoglobin and Carboxyhemoglobin Measurements Using Pulse Co-Oximeter in Healthy Dogs

Veterinary Medicine: Research and Reports
Jiwoong Her,1,2 Justin Roh,1 Deborah A Keys3 1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA; 2Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State
Her J, Roh J, Keys DA
doaj  

Nocturnal Hypoxemia Burden Correlates With Vestibular Dysfunction in Obstructive Sleep Apnea

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a potential contributor to vestibular dysfunction, though specific correlating parameters remain unclear. This study aimed to determine whether hypoxemia severity indices correlate quantitatively with caloric slow‐phase eye velocity (SPV), a marker of vestibular function. Methods In a retrospective
Dachan Kim, Seong Hoon Bae, Hyung‐Ju Cho   +2 more
wiley   +1 more source

Acute and sudden death secondary to cardiac tamponade during anaesthetic recovery in a 21‐year‐old draught mule

Equine Veterinary Education, EarlyView.
Summary This case report is of educational value and contributes to the literature because it describes a unique death after anaesthesia due to cardiac tamponade from a rare cardiac neoplasm. In trying to diagnose the origin of chronic sinusitis, a geriatric mule mare was anaesthetised and during recovery, died acutely.
A. Carroll, J. Quandt, S. Dantino
wiley   +1 more source

Anaesthetic management of a horse with acute kidney injury

Equine Veterinary Education, EarlyView.
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley   +1 more source

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

The FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga, Zsolt Ráduly, Beáta Boros‐Oláh, Éva Nagy, Zsolt Karányi, László Halász, Bálint László Bálint, György Vámosi, Emese Tóth, Péter Bai, Serena Santangelo, Patrizia Bossolasco, Antonia Ratti, Vincent Géli, Yves Pommier, Lóránt Székvölgyi   +15 more
wiley   +1 more source

Carbon Monoxide Poisoning: Diagnosis, Prognostic Factors, Treatment Strategies, and Future Perspectives

Diagnostics
Carbon monoxide (CO) poisoning is a significant public health issue, with diagnosis often complicated by non-specific symptoms and limited access to specialised tools. Early detection is vital for preventing long-term complications.
Mohd Afzal, Shagun Agarwal, Rabab H. Elshaikh, Asaad M. A. Babker, Ranjay Kumar Choudhary, Pranav Kumar Prabhakar, Farhana Zahir, Ashok Kumar Sah   +7 more
doaj   +1 more source

Randomized clinical trial to determine the effectiveness of CO-oximetry and anti-smoking brief advice in a cohort of kidney transplant patients who smoke. [PDF]

Int J Med Sci, 2020
Seijo-Bestilleiro R, Seoane-Pillado T, Pertega-Diaz S, González-Martín C, Valdes-Cañedo F, Balboa-Barreiro V, Fernandez-Rivera C, Alonso-Hernandez A, Cao-Vilariño M, Gil-Guillen V, Garcia-Rodriguez MT.   +10 more
europepmc   +1 more source