Results 181 to 190 of about 31,890,449 (349)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Process combination for mechanical co-processing of residues from municipal solid waste treatment. [PDF]

open access: yesWaste Manag Res
Demschar P   +4 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Royalty Reports: Moffat, Yard & Co., January 31, 1910

open access: yes, 1910
Royalty Reports for works published by Moffat Yard & Co., January ...
Moffat, Yard & Co.
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Queensland [cartographic material].

open access: yes, 1890
Map of the southern half of Queensland showing towns, districts, counties and railways with relief shown by hachures.; Plate [7] from: Pearson's Australasian school atlas. Library ed. Melbourne : J.W.
J. W. Pearson & Co.
core  

Evaluation of a fluidised catalytic cracking co-processing method for the production of renewable fuels using Category 3 animal fat and used cooking oils. [PDF]

open access: yesEFSA J
EFSA Panel on Biological Hazards (BIOHAZ)   +20 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Recent Advancements in Co-Processed Excipients

open access: yes
The primary objective of this review article aims to offer a thorough analysis among the most current advancements in excipient technology and its formulation techniques. It's impossible for one excipient to meet every performance requirement required to transform a drug's active component into a particular pharmaceutical formulation.
openaire   +1 more source

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