Results 241 to 250 of about 1,797,050 (302)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Harmonising Definitions of Multiple Long Terms Conditions for Inflammation Research: A Co-Production Approach

open access: yes
Asfaw D   +7 more
europepmc   +1 more source

Co-production in HIV research: a case study from the COVID-19 pandemic. [PDF]

open access: yesRes Involv Engagem
Papageorgiou V   +7 more
europepmc   +1 more source

Co-production in sleep research: A scoping review of current practices and future directions. [PDF]

open access: yesJ Sleep Res
Gale EL   +6 more
europepmc   +1 more source

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